Tag Archives: Prof Leonard Jason

Depression-like symptoms in ME research – invitation to participate

Prof Leonard Jason writes on Facebook, 14 October 2016: Our recent paper “Mortality in patients with ME and CFS” found patients are significantly at risk for earlier all-cause mortality with the top three causes of death being suicide, cardiovascular problems, and … Continue reading

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Increased risk of mortality in patients with ME & CFS

Research abstract: Background: There is a dearth of research examining mortality in individuals with myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS). Some studies suggest there is an elevated risk of suicide and earlier mortality compared to national norms. However, findings are inconsistent. Objective: … Continue reading

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Patient perceptions regarding possible changes to the name & criteria for CFS & ME

Research article abstract: For decades, researchers and patients have been debating the terms and criteria for chronic fatigue syndrome (CFS) and myalgic encephalomyelitis (ME). This has led to considerable difficulties in clearly communicating to the public the nature of these … Continue reading

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Post-exertional malaise: an exploratory factor analysis

Research abstract: Post-exertional malaise is a cardinal symptom of myalgic encephalomyelitis and chronic fatigue syndrome. There are two differing focuses when defining post-exertional malaise: a generalized, full-body fatigue and a muscle-specific fatigue. This study aimed to discern whether post-exertional malaise … Continue reading

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Assessing reduction in activity levels in ME/CFS

Research abstract: Background: Myalgic encephalomyelitis and chronic fatigue syndrome have case definitions with varying criteria, but almost all criteria require an individual to have a substantial reduction in activity level. Unfortunately, a consensus has not been reached regarding what constitutes substantial … Continue reading

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The role of infectious and stress-related onsets in ME & CFS

Research abstract: This study examined how the mode of onset for myalgic encephalomyelitis and chronic fatigue syndrome (ME and CFS) impacts patients’ presenting symptomatology. Specifically, this study investigated the differences between the most commonly reported ME and CFS onsets: infectious, … Continue reading

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Methods of evaluating ME interventions

Research abstract: INTRODUCTION The current study provides data from two patients with myalgic encephalomyelitis, who charted several of their symptoms over time. CASE PRESENTATION Each patient charted domains that were relevant to them, and they were attempting to assess the … Continue reading

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Comparing the DePaul Symptom Questionnaire with doctors’assessments

Research abstract: Background: Diagnostic assessment of chronic fatigue syndrome (CFS) and myalgic encephalomyelitis (ME) is largely based on a two part process; screening patients who might meet criteria and following up this assessment with physicians’ clinical evaluation of a range … Continue reading

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Developing case definitions for ME and CFS using practical experience and consensus

Research abstract: Background: There has been considerable controversy regarding how to name and define the illnesses known as myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS). The Institute of Medicine (IOM) report has proposed new clinical criteria and a new name for this … Continue reading

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ME: symptoms & biomarkers

Review abstract: Myalgic Encephalomyelitis (ME) continues to cause significant morbidity worldwide with an estimated one million cases in the United States. Hurdles to establishing consensus to achieve accurate evaluation of patients with ME continue, fueled by poor agreement about case definitions, slow progress … Continue reading

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