Tag Archives: rituximab

To future GPs – psychosomatic should not be the default suspicion re ME/CFS

Time to swot up on chronic fatigue – Future general practitioners need to be made aware that “psychosomatic” should not be the default suspicion, by Michael Brooks in the New Statesman, Nov 12 2015 Around 250,000 people in the UK suffer from … Continue reading

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Cancer doctor Dagfinn Øgreid has treated ME patients with rituximab

Blog article: Offers private ME treatment with cancer drugs – scientists react, by Anne Grete Storvik, Nov 23 2015 in Dagensmedicin [ translated by Google translate] A private clinic in Sandnes offers treatment for ME with the cancer drug rituximab. Patients pay … Continue reading

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UK rituximab trial fundraising total almost reached

Invest in ME has announced the latest fundraising total for the rituximab/B-cell research, which is a great boost as the research team at UCL are about to visit and discuss the subject with Dr Fluge and Professor Mella in Haukeland University Hospital, … Continue reading

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Elevated autoantibodies found in CFS subgroup

Research highlights: β adrenergic and muscarinic acetylcholine receptor autoantibodies are elevated in a subset of patients with Chronic Fatigue Syndrome (CFS). Elevated autoantibodies in CFS correlate with elevated IgG1-3 subclass levels, thyreoperoxidase and ANA antibodies and T cell activation. In … Continue reading

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Rituximab leads to B-cell depletion and remission in ME/CFS

Research abstract: Background: Myalgic Encephalopathy/Chronic Fatigue Syndrome (ME/CFS) is a disease of unknown etiology. We previously reported a pilot case series followed by a small, randomized, placebo-controlled phase II study, suggesting that B-cell depletion using the monoclonal anti-CD20 antibody rituximab … Continue reading

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Rituximab interviews

Two Norwegian scientists, Øystein Fluge and Olav Mella, who have been researching the effects of an anti-lymphoma drug called Rituximab on people with ME/CFS, talked about their work on the BBC Radio Cambridgeshire programme ‘Naked Scientists’ on Sunday, 22 March. … Continue reading

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Anti-inflammatory drugs and CFS/ME

Richard N. Podell M.D., MPH discusses the implications of Japanese research which found inflammation in the brain on the prohealth website: For most people with Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis (CFS/ME) central nervous system function is abnormal. However, we don’t understand the … Continue reading

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Norwegian Rituximab trial update

The Norwegian multicenter Rituximab study begins The long-awaited Norwegian phase III study of Rituximab as a treatment for ME/CFS is now getting off the ground. The study is led by the oncologists Prof Olav Mella and Dr Øystein Fluge at … Continue reading

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Immunostimulants – an alternative treatment to rituximab

Abstract Chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) has long been associated with the presence of infectious agents, but no single pathogen has been reliably identified in all patients with the disease. Recent studies using metagenomic techniques have demonstrated the presence … Continue reading

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Rituximab UK trial update

Invest in ME have now raised £57,000 for their UK rituximab trial from a variety of organisations and individuals and can begin the first phase. The UCL team is working on a study to confirm and expand Dr Bansal’s B cell results … Continue reading

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