Category Archives: News

The relationship between IBS, dyspepsia, chronic fatigue and overactive bladder syndrome

Research article abstract: Background: To investigate in a cohort with previous gastrointestinal infection and a control group the prevalence of overactive bladder syndrome (OAB), and how it was associated with three other functional disorders; irritable bowel syndrome (IBS), functional dyspepsia … Continue reading

Posted in News | Tagged , , , , , , | Comments Off on The relationship between IBS, dyspepsia, chronic fatigue and overactive bladder syndrome

Fatigue is prevalent and debilitating in patients with mitochondrial disease

Highlights Perceived fatigue is a prominent and often debilitating symptom in patients with mitochondrial disease. Perceived fatigue correlates with disease severity but not genotype. Excessive sleepiness is prevalent but dissociated with perceived fatigue in patients with mitochondrial disease. Perceived fatigue … Continue reading

Posted in News | Tagged , , , | Comments Off on Fatigue is prevalent and debilitating in patients with mitochondrial disease

Dysfunctional energy metabolism and oxidative stress pathways in CFS

Research abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating long-term multisystem disorder with a central and inexplicably persistent fatigue symptom that is unable to be relieved by rest. Energy metabolism and oxidative stress have been recent focal points of … Continue reading

Posted in News | Tagged , , | Comments Off on Dysfunctional energy metabolism and oxidative stress pathways in CFS

The effect of submaximal exercise tests in ME/CFS

Research abstract: BACKGROUND Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating illness. Symptoms include profound fatigue and distinctive post-exertional malaise (PEM). We asked whether a submaximal exercise test would prove useful for identifying different patterns of tissue oxygen utilization in … Continue reading

Posted in News | Tagged , , | Comments Off on The effect of submaximal exercise tests in ME/CFS

Dysfunction found in innate and adaptive immune systems in CFS/ME

Research abstract: Background: Abnormal immune function is often an underlying component of illness pathophysiology and symptom presentation. Functional and phenotypic immune-related alterations may play a role in the obscure pathomechanism of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). The objective of this … Continue reading

Posted in News | Tagged , , , , | Comments Off on Dysfunction found in innate and adaptive immune systems in CFS/ME

Computerised training improves verbal working memory in ME/CFS

Research abstract: OBJECTIVE: Patients with myalgic encephalomyelitis/chronic fatigue syndrome experience cognitive difficulties. The aim of this study was to evaluate the effect of computerized training on working memory in this syndrome. DESIGN: Non-randomized (quasi-experimental) study with no-treatment control group and … Continue reading

Posted in News | Tagged , | Comments Off on Computerised training improves verbal working memory in ME/CFS

Case study of yoga and CFS

Case study abstract: BACKGROUND AND OBJECTIVE: Chronic Fatigue Syndrome (CFS) is characterized by excessive fatigue after minimal physical or mental exertion, muscle and joint pain, poor concentration, dizziness, and sleep disturbances. We report here the effect of a yoga-based lifestyle intervention … Continue reading

Posted in News | Tagged , | Comments Off on Case study of yoga and CFS

Variability in symptoms complicates usefulness of case definitions

Research abstract: Background: Ambiguities in case definitions have created difficulties in replicating findings and estimating the prevalence rates for chronic fatigue syndrome (CFS) and Myalgic Encephalomyelitis (ME). Purpose: The current study examined differences in occurrence rates for CFS and ME … Continue reading

Posted in News | Tagged , , , | Comments Off on Variability in symptoms complicates usefulness of case definitions

Potential value of cassia bark for CFS

Research abstract: The fruit of Cassia fistula Linn. is a legume, has antioxidant and lots of other medicinal properties. As oxidants are involved in the pathogenesis of chronic fatigue syndrome, the present study was done to evaluate the effect of … Continue reading

Posted in News | Tagged , , | Comments Off on Potential value of cassia bark for CFS

Genes disrupt signalling mechanisms in CFS

Research abstract: Background: The transient receptor potential (TRP) superfamily in humans comprises 27 cation channels with permeability to monovalent and divalent cations. These channels are widely expressed within humans on cells and tissues and have significant sensory and regulatory roles … Continue reading

Posted in News | Tagged , , , , | Comments Off on Genes disrupt signalling mechanisms in CFS