Category Archives: News
Autoimmune basis for Postural Tachycardia Syndrome
Abstract BACKGROUND Patients with postural tachycardia syndrome (POTS) have exaggerated orthostatic tachycardia often following a viral illness, suggesting autoimmunity may play a pathophysiological role in POTS. We tested the hypothesis that they harbor functional autoantibodies to adrenergic receptors (AR). METHODS … Continue reading
WAMES AGM 1st April
The WAMES AGM will take place on 1st April in Dinas Powys. This will be a short business meeting to report on the activities of the past year and plan the priorities for the coming year. Contact Jan if you … Continue reading
The role of the HPA-axis in adolescent CFS
Abstract BACKGROUND: There is accumulating evidence of hypothalamic-pituitary-adrenal (HPA) axis hypofunction in chronic fatigue syndrome (CFS). However, knowledge of this hypofunction has so far come exclusively from research in adulthood, and its clinical significance remains unclear. The objective of the … Continue reading
Immune dysregulation in CFS similar to autoimmune disorders
Abstract Perturbations in immune processes are a hallmark of a number of autoimmune and inflammatory disorders. Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is an inflammatory disorder with possible autoimmune correlates, characterized by reduced NK cell activity, elevations in regulatory T cells … Continue reading
Immune dysfunction worse in severe CFS patients
Abstract Objective: Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a disabling illness, characterized by persistent, debilitating fatigue and a multitude of symptoms. Immunological alterations are prominent in CFS/ME cases, however little is known about the relationship between CFS/ME severity and the … Continue reading
Adverse effects of antidepressants greater than reported
Abstract Background In the context of rapidly increasing antidepressant (AD) use internationally, and recent reviews raising concerns about efficacy and adverse effects, this study aimed to survey the largest sample of AD recipients to date. Methods An online questionnaire about … Continue reading
Medications cause 70% of dry eyes, mouth etc. in CFS
Chronic fatigue syndrome (CFS) is a heterogeneous and multisystemic disorder of unknown pathogenesis and etiology. It is characterized by prolonged generalized and abnormal fatigue post-exercise (98%), recurrent headache (90%) and problems of concentration and memory (85%) that have lasted for … Continue reading
Cognitive dysfunction causes fatigue and depression in ME/CFS
Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by persistent emotional, mental, and physical fatigue accompanied by a range of neurological, autonomic, neuroendocrine, immune, and sleep problems. Research has shown that psychosocial factors such as anxiety and depression as … Continue reading
