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Central nervous system findings in CFS
Review abstract: CNS findings in chronic fatigue syndrome and a neuropathological case report Kimberly Ferrero, Mitchell Silver, Alan Cocchetto, Eliezer Masliah, Dianne Langford in Journal of Investigative Medicine Vol 65 Issue 4 [published 6 April 2017] Chronic fatigue syndrome (CFS) is characterized as a persistent, debilitating complex disorder of unknown … Continue reading
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Tagged Alan Cocchetto, autopsy, Central Nervous System, CNS, Dr Dianne Langford, Eliezer Masliah, Kimberly Ferrero, Mitchell Silver, white matter
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Roles of the right dorsolateral prefrontal cortex during physical fatigue: a magnetoencephalographic study
Research abstract: Background: A regulation system in the central nervous system plays an important role in controlling physical performance during physical fatigue. Purpose: To clarify the neural mechanisms of this regulation system during physical fatigue using magnetoencephalography (MEG) and a … Continue reading
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Tagged Central Nervous System, CNS, DLPFC, dorsolateral prefrontal cortex, fatigue, magnetoencephalography, Masaaki Tanaka, MEG
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Immune activation in the central nervous system of ME/CFS found by cytokine network analysis of cerebrospinal fluid
Research abstract: Myalgic encephalomyelitis/chronic fatigue syndrome is an unexplained debilitating disorder that is frequently associated with cognitive and motor dysfunction. We analyzed cerebrospinal fluid from 32 cases, 40 subjects with multiple sclerosis and 19 normal subjects frequency-matched for age and … Continue reading
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Tagged C.G. Gottschalk, Central Nervous System, cerebrospinal fluid, CNS, cytokines, Dr Daniel Peterson, immune activation, Prof Ian Lipkin, Prof Mady Hornig
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Brain-derived neurotrophic factor concentration may not be depressed in CFS
Research abstract: Due to its effect on the central nervous system, brain-derived neurotrophic factor (BDNF) has been hypothesized to be involved in a number of neurodegenerative and psychiatric disorders. Recently, BDNF was also reported to be significantly lower in patients … Continue reading
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Tagged BDNF, brain derived neurotrophic factor, Central Nervous System, CNS
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A review of grey matter volume research in CFS
Review article abstract: Chronic fatigue syndrome (CFS) is a debilitating and complex disorder characterized by profound fatigue with uncertain pathologic mechanism. Neuroimage may be an important key to unveil the central nervous system (CNS) mechanism in CFS. Although most of … Continue reading
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Tagged brain, Central Nervous System, grey matter volume, neuroimaging
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Human herpesvirus 6 and the nervous system
Human herpesvirus (HHV)-6 is a β-herpesvirus that infects most infants by 2 years of age and persists in a variety of host cells after primary infection, with intermittent reactivation typically during periods of immunosuppression. HHV-6 has two closely related species, … Continue reading
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Tagged Central Nervous System, CNS, HHV-6, Human herpesvirus 6
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Lixdexamfetamine dimesylate helps functioning, fatigue and pain in CFS subgroup
A drug commonly used for ADHD (Attention deficit hyperactivity disorder) has been trialled by JL Young in the USA. Lixdexamfetamine dimesylate is in the amphetamine family and is rapidly absorbed into the body and converted to dextroamphetamine, which is responsible … Continue reading
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Tagged ADHD, amphetamine, Central Nervous System, CNS, JL Young, Lixdexamfetamine dimesylate
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