Tag Archives: Dr Leighton Barnden

Research: fMRI reveals differences between ME/CFS diagnostic criteria

fMRI distinguishes between two classes of ME/CFS   Australian researchers have discovered that patients diagnosed using 2 different criteria, International Consensus Criteria (ICC) and the Fukuda criteria, have different brain activity. The main difference between the 2 criteria is that … Continue reading

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Cognitive dysfunction research: Hippocampal subfields & ME/CFS

Volumetric differences in hippocampal subfields and associations with clinical measures in myalgic encephalomyelitis/chronic fatigue syndrome, by Kiran Thapaliya, Donald Staines, Sonya Marshall- Gradisnik, Jiasheng Su, Leighton Barnden in Journal of Neuroscience Research March 31, 2022     “The hippocampus is … Continue reading

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Research: Diffusion tensor imaging (MRI) reveals neuronal microstructural changes in ME/CFS

Diffusion tensor imaging reveals neuronal microstructural changes in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, by Kiran Thapaliya, Sonya Marshall-Gradisnik, Don Staines, Leighton Barnden in European Journal of Neuroscience, August 6, 2021 [doi/10.1111/ejn.15413]   Research abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients suffer from … Continue reading

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Mapping of pathological change in CFS using the ratio of T1- & T2-weighted MRI scans

Mapping of pathological change in chronic fatigue syndrome using the ratio of T1- and T2-weighted MRI scans, by Kiran Thapaliya, Sonya Marshall-Gradisnik, Don Staines, Leighton Barnden in NeuroImage: Clinical Vol 28, 2020, 102366 [doi.org/10.1016/j.nicl.2020.102366]   Research highlights We showed increased … Continue reading

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A systematic review of neurological impairments in ME/CFS using neuroimaging techniques

A systematic review of neurological impairments in myalgic encephalomyelitis/ chronic fatigue syndrome using neuroimaging techniques, by Rebekah Maksoud, Stanley du Preez, Natalie Eaton-Fitch, Kiran Thapaliya, Leighton Barnden, Hélène Cabanas, Donald Staines, Sonya Marshall-Gradisnik in PLoS One 2020 Apr 30;15(4) [doi:10.1371/journal.pone.0232475.   … Continue reading

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Intra brainstem connectivity is impaired in CFS

Intra brainstem connectivity is impaired in chronic fatigue syndrome, by Leighton R Barnden, Zack Y Shan, Donald R Staines, Sonya Marshall-Gradisnik, Kevin Finegan, Timothy Ireland, Sandeep Bhuta, in NeuroImage: Clinical Vol 24, 2019, [https://doi.org/10.1016/j.nicl.2019.102045]   Research highlights: RAS connectivity was … Continue reading

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Hyperintense sensorimotor T1 spin echo MRI is associated with brainstem abnormality in CFS

Hyperintense sensorimotor T1 spin echo MRI is associated with brainstem abnormality in CFS by Leighton R. Barnden, Zack Y. Shan, Donald R Staines, Sonya Marshall-Gradisnik, Kevin Finegan, Timothy Ireland, Sandeep Bhuta, in NeuroImage: Clinical Volume 20, 2018, Pages 102-109 Research abstract: We recruited 43 Chronic … Continue reading

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Brain function characteristics of CFS

Research abstract: Brain function characteristics of chronic fatigue syndrome: A task fMRI study, by Zack Y Shan, Kevin Finegan, Sandeep Bhutab, Timothy Ireland, Donald R Staines, Sonya M.Marshall-Gradisnik, Leighton R.Barnden in NeuroImage: Clinical Vol 19, 2018, Pages 279-286 Highlights CFS … Continue reading

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Decreased connectivity & increased BOLD complexity in the default mode network in CFS

Research abstract: Decreased connectivity and increased BOLD complexity in the default mode network in individuals with chronic fatigue syndrome, by ZY Shan, K Finegan, S Bhuta, T Ireland, DR Staines, SM Marshall-Gradisnik, LR Barnden in Brain Connect. 2017 Nov 20 … Continue reading

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ME/CFS studies link autonomic nervous system problems to brain

Health rising blog post, by Cort Johnson, 3 Feb 2017: Chronic Fatigue Syndrome Studies Link Autonomic Nervous System Problems to Brain Dr. Barnden of the National Centre for NeuroImmnology and Emerging Diseases (NCNED) in Griffith University, Australia has been doing … Continue reading

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