Tag Archives: white matter

Research review: Brainstem abnormalities in ME/CFS… evaluation of MRI findings

Brainstem abnormalities in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A scoping review and evaluation of Magnetic Resonance Imaging findings, by Todd Nelson, Lan-Xin Zhang, Hui Guo, Luis Nacul, Xiaowei Son in Frontiers in Neurology Vol 12, p 769511, Dec 2021 [doi:10.3389/fneur.2021.769511]   Review … Continue reading

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Mapping of pathological change in CFS using the ratio of T1- & T2-weighted MRI scans

Mapping of pathological change in chronic fatigue syndrome using the ratio of T1- and T2-weighted MRI scans, by Kiran Thapaliya, Sonya Marshall-Gradisnik, Don Staines, Leighton Barnden in NeuroImage: Clinical Vol 28, 2020, 102366 [doi.org/10.1016/j.nicl.2020.102366]   Research highlights We showed increased … Continue reading

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Grey and white brain matter differences in CFS

Research abstract: Grey and white matter differences in Chronic Fatigue Syndrome – a voxel-based morphometry study, by Andreas Finkelmeyer, Jiabao He, Laura Maclachlan, Stuart Watson, Peter Gallagher, Julia L. Newton, Andrew M. Blamire in NeuroImage: Clinical, Volume 17, 2018, Pages 24-30 [Preprint Available online 28 September … Continue reading

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Central nervous system findings in CFS

Review abstract: CNS findings in chronic fatigue syndrome and a neuropathological case report Kimberly Ferrero, Mitchell Silver, Alan Cocchetto, Eliezer Masliah, Dianne Langford in Journal of Investigative Medicine Vol 65 Issue 4 [published 6 April 2017] Chronic fatigue syndrome (CFS) is characterized as a persistent, debilitating complex disorder of unknown … Continue reading

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ME/CFS studies link autonomic nervous system problems to brain

Health rising blog post, by Cort Johnson, 3 Feb 2017: Chronic Fatigue Syndrome Studies Link Autonomic Nervous System Problems to Brain Dr. Barnden of the National Centre for NeuroImmnology and Emerging Diseases (NCNED) in Griffith University, Australia has been doing … Continue reading

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Six year study of abnormal brain changes in ME/CFS

ME Australia blog post, by  Sasha Nimmo, 12 July 2016: Six year study of abnormal brain changes in chronic fatigue syndrome patients An Australian six year study evaluating progressive brain changes associated with chronic fatigue syndrome (Fukuda and Canadian Consensus … Continue reading

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Brain white matter abnormalities in ME/CFS

ME Research UK research article, by Dr Neil Abbot, 25 May 2016: White matter abnormalities Most studies in ME/CFS are cross-sectional in nature – researchers look at patients and controls at one point in time and make comparisons between the … Continue reading

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Progressive brain changes in patients with CFS

Research abstract: PURPOSE: To examine progressive brain changes associated with chronic fatigue syndrome (CFS). MATERIALS AND METHODS: We investigated progressive brain changes with longitudinal MRI in 15 CFS and 10 normal controls (NCs) scanned twice 6 years apart on the same … Continue reading

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Fatigue may involve abnormal function of the motor system

Research abstract: Although the prevalence of chronic fatigue is approximately 20% in healthy individuals, there are no studies of brain structure that elucidate the neural correlates of fatigue outside of clinical subjects. We hypothesized that fatigue without evidence of disease … Continue reading

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MRI shows differences between CFS and depression

Research article: White matter (WM) involvement in chronic fatigue syndrome (CFS) was assessed using voxel-based regressions of brain MRI against CFS severity scores and CFS duration in 25 subjects with CFS and 25 normal controls (NCs). As well as voxel-based … Continue reading

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