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Hypothesis: Broken connections: the evidence for neuroglial failure in ME/CFS
Broken Connections: The evidence for neuroglial failure in ME/CFS, by Herbert Renz-Polster, MD, Dorothee Bienzle, PhD 31 Aug 2021 [doi:10.31219/osf.io/ef3n4] Review abstract: In spite of decades of research, the pathobiology of Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS) is still … Continue reading
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Tagged Central Nervous System, CNS, Dorothee Bienzle, Dr Herbert Renz-Polster, neuroglia, neuroimmune dysfunction
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Using plasma autoantibodies of Central Nervous System proteins to distinguish veterans with Gulf War Illness from healthy & symptomatic controls
Using plasma autoantibodies of Central Nervous System proteins to distinguish veterans with Gulf War Illness from healthy and symptomatic controls, by Mohamed B Abou-Donia, Elizabeth S Lapadula, Maxine H Krengel, Emily Quinn, Jessica LeClair, Joseph Massaro, Lisa A Conboy, Efi Kokkotou, … Continue reading
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Tagged biomarker, Central Nervous System, CNS, Daniel D Nguyen, Dr Nancy Klimas, Efi Kokkotou, Elizabeth S Lapadula, Emily Quinn, Jessica LeClair, Joseph Massaro, Kimberly Sullivan, Lisa A Conboy, Maria Abreu, Maxine H Krengel, Mohamed B Abou-Donia, Neurodegeneration Index, plasma autoantibodies
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The putative glymphatic signature of CFS
The putative glymphatic signature of CFS: A new view on the disease pathogenesis and therapy, by Peter Wostyn, Peter Paul De Deyn in Medical Hypotheses Sept 2018, Vol 118, Pages 142–145 Abstract: The underlying pathophysiology of chronic fatigue syndrome remains incompletely understood and there … Continue reading
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Tagged Central Nervous System, CNS, glymphatic dysfunctioon, lumboperitoneal shunting, Peter Paul De Deyn, Peter Wostyn
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Transient Receptor Potential Ion channels in the etiology & pathomechanism of CFS/ME
Research abstract: Transient Receptor Potential Ion Channels in the Etiology and Pathomechanism of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis, by Donald Staines, S Du Preez, H Cabanas, C Balinas, N Eaton, R Passmore, R Maksoud, J Redmayne, S Marshall-Gradisnik in International Journal … Continue reading
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Tagged calcium signaling, Cassandra Balinas, Central Nervous System, CNS, Dr Sonya Marshall-Gradisnik, Hélène Cabanas, J Redmayne, Natalie Eaton, Prof Donald Staines, R Maksoud, R Passmore, S Du Preez, Transient Receptor Potential Ion Channels
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Central nervous system findings in CFS
Review abstract: CNS findings in chronic fatigue syndrome and a neuropathological case report Kimberly Ferrero, Mitchell Silver, Alan Cocchetto, Eliezer Masliah, Dianne Langford in Journal of Investigative Medicine Vol 65 Issue 4 [published 6 April 2017] Chronic fatigue syndrome (CFS) is characterized as a persistent, debilitating complex disorder of unknown … Continue reading
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Tagged Alan Cocchetto, autopsy, Central Nervous System, CNS, Dr Dianne Langford, Eliezer Masliah, Kimberly Ferrero, Mitchell Silver, white matter
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Roles of the right dorsolateral prefrontal cortex during physical fatigue: a magnetoencephalographic study
Research abstract: Background: A regulation system in the central nervous system plays an important role in controlling physical performance during physical fatigue. Purpose: To clarify the neural mechanisms of this regulation system during physical fatigue using magnetoencephalography (MEG) and a … Continue reading
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Tagged Central Nervous System, CNS, DLPFC, dorsolateral prefrontal cortex, fatigue, magnetoencephalography, Masaaki Tanaka, MEG
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Immune activation in the central nervous system of ME/CFS found by cytokine network analysis of cerebrospinal fluid
Research abstract: Myalgic encephalomyelitis/chronic fatigue syndrome is an unexplained debilitating disorder that is frequently associated with cognitive and motor dysfunction. We analyzed cerebrospinal fluid from 32 cases, 40 subjects with multiple sclerosis and 19 normal subjects frequency-matched for age and … Continue reading
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Tagged C.G. Gottschalk, Central Nervous System, cerebrospinal fluid, CNS, cytokines, Dr Daniel Peterson, immune activation, Prof Ian Lipkin, Prof Mady Hornig
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Brain-derived neurotrophic factor concentration may not be depressed in CFS
Research abstract: Due to its effect on the central nervous system, brain-derived neurotrophic factor (BDNF) has been hypothesized to be involved in a number of neurodegenerative and psychiatric disorders. Recently, BDNF was also reported to be significantly lower in patients … Continue reading
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Tagged BDNF, brain derived neurotrophic factor, Central Nervous System, CNS
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