Tag Archives: gene expression

Gene expression factor analysis used to differentiate CFS, FM and depression

Research abstract: OBJECTIVE: To determine if independent candidate genes can be grouped into meaningful biologic factors, and whether these factors are associated with the diagnosis of chronic fatigue syndrome (CFS) and fibromyalgia syndrome (FMS), while controlling for comorbid depression, sex, … Continue reading

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MicroRNAs as potential biomarkers in ME/CFS

ME Research UK comments on recent research: MicroRNAs hsa-miR-99b, hsa-miR-330, hsa-miR-126 and hsa-miR-30c: Potential Diagnostic Biomarkers in Natural Killer (NK) Cells of Patients with Chronic Fatigue Syndrome (CFS)/ Myalgic Encephalomyelitis (ME), by RD Petty, NE McCarthy, R Le Dieu, J R … Continue reading

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Potential diagnostic biomarkers in Natural Killer cells of patients with CFS/ ME

Research abstract: BACKGROUND: Chronic Fatigue Syndrome (CFS/ME) is a complex multisystem disease of unknown aetiology which causes debilitating symptoms in up to 1% of the global population. Although a large cohort of genes have been shown to exhibit altered expression … Continue reading

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Prof George Davey Smith calls for large scale ME/CFS genetic studies

Prof George Davey Smith, a clinical epidemiologist at the university of Bristol, says there is a need for large scale genetic studies of ME/CFS as it is not possible to draw accurate conclusions from small scale studies. Simon McGrath reports on Prof … Continue reading

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Gene expression can differentiate CFS, FM and depression

Research abstract: OBJECTIVE To determine if independent candidate genes can be grouped into meaningful biological factors and if these factors are associated with the diagnosis of chronic fatigue syndrome (CFS) and fibromyalgia (FMS) while controlling for co-morbid depression, sex, and age. … Continue reading

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Prof Alan Light videos on fatigue and gene expression in ME/CFS

Professor Alan Light, from Utah University, talks about his involvement with ME  in videos posted on the Dutch Youtube site ME/cvs Vereniging. no. 58  Fatigue – the differences between generalised fatigue and the fatigue of ME/CFS no. 59  Genes & gene expression &  … Continue reading

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Rituximab interviews

Two Norwegian scientists, Øystein Fluge and Olav Mella, who have been researching the effects of an anti-lymphoma drug called Rituximab on people with ME/CFS, talked about their work on the BBC Radio Cambridgeshire programme ‘Naked Scientists’ on Sunday, 22 March. … Continue reading

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Video presentation of Alan Light’s gene expression research

“Using Gene Expression to Objectively Subset & Diagnose FM, CFS and Depression”  Published on Dec 18, 2014 Alan Light, PhD gave this presentation during OFFER’s 2014 Healthcare Provider Conference. In this study, they looked at 46 genes [using the leukocytes] … Continue reading

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Fatigue in MS and ME: similarities and differences

Cort Johnson in his blog Health rising asks if the fatigue found in MS and ME is similar or different: Simply looking at the symptoms indicated that MS is primarily a fatiguing disorder, and that MS patients may, in fact, … Continue reading

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SNPs in CFS/ME genes could lead to diagnostic test for CFS/ME subtypes

Research abstract Aims We have reported gene expression changes in patients with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and the fact that such gene expression data can be used to identify subtypes of CFS/ME with distinct clinical phenotypes. Due to the … Continue reading

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