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Autoimmunity-related risk variants in PTPN22 & CTLA4 are associated with ME/CFS with infectious onset
Autoimmunity-related risk variants in PTPN22 and CTLA4 are associated with ME/CFS with infectious onset, by Sophie Steiner, Sonya C Becker, Jelka Hartwig, Franziska Sotzny, Sebastian Lorenz, Sandra Bauer, Madlen Löbel, Anna B Stittrich, Patricia Grabowski and Carmen Scheibenbogen in Front. Immunol., … Continue reading
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Tagged Anna B Stittrich, autoimmune disorders, Carmen Scheibenbogen, Franziska Sotzny, genes, Jelka Hartwig, Madlen Löbel, Patricia Grabowski, Sandra Bauer, Sebastian Lorenz, single nucleotide polymorphisms, SNPs, Sonya C Becker, Sophie Steiner, T cell activation
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Human Leukocyte Antigen alleles associated with ME/CFS
Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), by Asgeir Lande, Øystein Fluge, Elin B Strand, Siri T Flåm, Daysi D Sosa, Olav Mella, Torstein Egeland, Ola D Saugsta, Benedicte A Lie, Marte K Viken in Scientific … Continue reading
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Tagged autoimmune disorders, Benedicte A Lie, Daysi D Sosa, Dr Oystein Fluge, Elin B Strand, genes, genotypes, HLA genes, human leukocyte antigen molecules, Marte K Viken, Ola D Saugsta, Prof Olav Mella, Siri T Flåm, Torstein Egeland
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New Australian genetic marker detection study
ME Research UK blog post, 6 November 2016: New study – Genetic marker detection Prof Brett Lidbury and colleagues at the John Curtin School of Medical Research, Australian National University in Canberra are conducting an ongoing programme, funded by charities in … Continue reading
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Tagged Australia, biomarkers, genes, ME Research UK, Prof Brett Lidbury
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The search for a genetic predisposition to ME/CFS
ME Research article, 26 February 2016: Genome-wide associations In human beings, a very small number of DNA gene sequences differ between individuals, and these consist largely of single nucleotide polymorphisms (SNPs, pronounced “snips”). While most SNPs are silent, others have … Continue reading
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Tagged genes, genetic predisposition, genome associations, ME Research UK, SNPs
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Invitation to take part in a large gene study of ME/CFS
Are you currently diagnosed with ME/CFS (SEID)? Are you interested in your genetic makeup? If so, help the INIM create a one of a kind genetic database for patients with ME/CFS. Participation for this study requires you to have a … Continue reading
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Tagged Dr Nancy Klimas, genes, genetic database, INIM, Institute for Neuro Immune Medicine, research
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Immune and inflammation related genes in CFS
Research abstract: Recent evidence suggests immune and inflammatory alterations are important in chronic fatigue syndrome (CFS). This study was done to explore the association of functionally important genetic variants in inflammation and immune pathways with CFS. Peripheral blood DNA was … Continue reading
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Tagged Elizabeth R. Unger, genes, immune dysfunction, inflammation
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Prof Alan Light videos on fatigue and gene expression in ME/CFS
Professor Alan Light, from Utah University, talks about his involvement with ME in videos posted on the Dutch Youtube site ME/cvs Vereniging. no. 58 Fatigue – the differences between generalised fatigue and the fatigue of ME/CFS no. 59 Genes & gene expression & … Continue reading
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Tagged chronic fatigue, gene expression, genes, ME/cvs Vereniging, Prof Alan Light
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Methylation may have role in immunological changes in CFS/ME
Abstract Objective: Methylation is known to regulate biological processes and alterations in methylation patterns have been associated with a variety of diseases. Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is an unexplained disorder associated with immunological and molecular changes. CD4+T cells specifically, … Continue reading