Tag Archives: mitochondrial dysfunction

The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders

Article abstract Background: Mitochondrial dysfunction and defects in oxidative metabolism are a characteristic feature of many chronic illnesses not currently classified as mitochondrial diseases. Examples of such illnesses include bipolar disorder, multiple sclerosis, Parkinson’s disease, schizophrenia, depression, autism, and chronic … Continue reading

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CFS subgroup found to have low level inflammation

CFS is characterized by profound levels of persistent/recurrent fatigue. It is proposed that chronic, low level inflammation may play a role in this fatigue. We recruited 100 untreated patients with CFS (average age 33±12) and 100 age and sex matched … Continue reading

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Mitochondrial dysfunction and fatigue review

Abstract Fatigue is often described by patients as a lack of energy, mental or physical tiredness, diminished endurance, and prolonged recovery after physical activity. Etiologic mechanisms underlying fatigue are not well understood; however, fatigue is a hallmark symptom of mitochondrial … Continue reading

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Possible causes of mitochondrial dysfunctions in ME

Abstract Myalgic encephalomyelitis / chronic fatigue syndrome (ME/cfs) is classified by the World Health Organization as a disorder of the central nervous system. ME/cfs is an neuro-immune disorder accompanied by chronic low-grade inflammation, increased levels of oxidative and nitrosative stress … Continue reading

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Mitochondrial dysfunction differs in CFS and FM

Research abstract Chronic fatigue syndrome (CFS) and fibromyalgia (FM) are complex and serious illnesses that affect approximately 2.5% and 5% of the general population worldwide, respectively. The etiology is unknown; however, recent studies suggest that mitochondrial dysfunction has been involved … Continue reading

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Dr Myhill’s protocol improves mitochondrial function and fatigue

The third in a series of studies on mitochondrial function in ME/CFS has been published. Having established in the first two papers that mitochondrial dysfunction is a central pathophysiological lesion in ME/CFS, the aim of the third study  was to … Continue reading

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Mitochondrial dysfunction found in ME/CFS

Abstract: The objectives of this study are to test the hypothesis that the fatigue and accompanying symptoms of Chronic Myalgic Encephalomyelitis/ Fatigue Syndrome are in part due to defects in energy provision at the cellular level, and to understand the … Continue reading

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