Tag Archives: oxidative stress

Central pathways causing fatigue in CFS

Article abstract Background The genesis of severe fatigue and disability in people following acute pathogen invasion involves the activation of Toll-like receptors followed by the upregulation of proinflammatory cytokines and the activation of microglia and astrocytes. Many patients suffering from … Continue reading

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The study of metabolism important for CFS research

Research abstract Chronic fatigue syndrome (CFS) is a poorly understood condition that presents as long-term physical and mental fatigue with associated symptoms of pain and sensitivity across a broad range of systems in the body. The poor understanding of the … Continue reading

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Vitamin D supplement doesn’t improve CFS/ME symptoms

Research abstract Highlights We randomised 50 patients with CFS/ME to receive six months of intermittent high-dose vitamin D or placebo. Vitamin D did not improve pulse-wave velocity or flow-mediated dilatation of the brachial artery compared to placebo. Vitamin D did … Continue reading

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Altered immune response to exercise in CFS/ME

Abstract An increasing number of studies have examined how the immune system of patients with Chronic Fatigue Syndrome (CFS), or myalgic encephalomyelitis, responds to exercise.   The objective of the present study was to systematically review the scientific literature addressing … Continue reading

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Multivitamin mineral supplementation helpful in CFS

Abstract Background Chronic fatigue syndrome (CFS) is characterized by medically unexplained persistent or reoccurring fatigue lasting at least 6 months. CFS has a multifactorial pathogenesis in which oxidative stress (OS) plays a prominent role. Treatment is with a vitamin and … Continue reading

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Possible causes of mitochondrial dysfunctions in ME

Abstract Myalgic encephalomyelitis / chronic fatigue syndrome (ME/cfs) is classified by the World Health Organization as a disorder of the central nervous system. ME/cfs is an neuro-immune disorder accompanied by chronic low-grade inflammation, increased levels of oxidative and nitrosative stress … Continue reading

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Mitochondrial dysfunction differs in CFS and FM

Research abstract Chronic fatigue syndrome (CFS) and fibromyalgia (FM) are complex and serious illnesses that affect approximately 2.5% and 5% of the general population worldwide, respectively. The etiology is unknown; however, recent studies suggest that mitochondrial dysfunction has been involved … Continue reading

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Oxidative stress and possible early signs of atherosclerosis in CFS

The abstract of a Serbian study: INTRODUCTION: Chronic fatigue syndrome (CFS) is a widely recognized problem, characterized by prolonged, debilitating fatigue and a characteristic group of accompanying symptoms, that occurs four times more frequently in women than in men. The … Continue reading

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