Tag Archives: oxidative stress

Relationship between exercise-induced oxidative stress changes & parasympathetic activity in CFS

Relationship between exercise-induced oxidative stress changes and parasympathetic activity in Chronic Fatigue Syndrome: an observational study in patients and healthy subjects, by Andrea Polli, Jessica Van Oosterwijck, Jo Nijs, Uros Marusic, Inge De Wandele, Lorna Paul, Mira Meeus , Greta … Continue reading

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Changes in the transcriptome of circulating immune cells of a N Z cohort with ME/CFS

Changes in the transcriptome of circulating immune cells of a New Zealand cohort with myalgic encephalomyelitis/chronic fatigue syndrome, by Eiren Sweetman, Margaret Ryan, Christina Edgar, Angus MacKay, Rosamund Vallings, Warren Tate in International Journal of Immunopathology and Pharmacology vol 33 2019 [Published … Continue reading

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The putative role of oxidative & inflammation in the pathophysiology of sleep dysfunction across neuropsychiatric disorders

Review summary: The putative role of oxidative stress and inflammation in the pathophysiology of sleep dysfunction across neuropsychiatric disorders: Focus on chronic fatigue syndrome, bipolar disorder and multiple sclerosis, by Gerwyn Morris, Brendon Stubbs, Cristiano A Köhlerx, Ken Walder, Anastasiya Slyepchenko, … Continue reading

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Hyperactive brain in CFS – neurometabolites in anterior cingulate cortex

Research abstract: Neurometabolites in anterior cingulate cortex in chronic fatigue syndrome: a magnetic resonance spectroscopy study at 7 Tesla, by Chi Chen, [Master’s Thesis, Oxford University Sep 2017] Background: Chronic fatigue syndrome (CFS) is a disorder characterized by prolonged physical and mental fatigue that … Continue reading

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Inflammation correlates with symptoms in CFS

Research overview abstract: Inflammation correlates with symptoms in chronic fatigue syndrome, by Anthony L Komaroff in PNAS August 15, 2017 It is not unusual for patients who say they are sick to have normal results on standard laboratory testing. The physician … Continue reading

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Post-exercise muscle fatigue, oxidative stress & CD26 expression correlate to impaired quality of life in ME/CFS

Research abstract: Background: Myalgic encephalomyelitis chronic fatigue syndrome (ME/CFS) is a common debilitating disorder associated with an intense fatigue, a reduced physical activity, and an impaired quality of life. There are no established biological markerof the syndrome. The etiology is … Continue reading

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Is CFS/ME autoimmune & inflammatory?

VeryWell blog post, by Adrienne Dellwo [Reviewed by a board-certified physician], 8 July 2016: Is Chronic Fatigue Syndrome Autoimmune & Inflammatory? What We Know About It You still hear that chronic fatigue syndrome (ME/CFS) is a “mystery illness,” but the nature … Continue reading

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A potential biomarker for fatigue: oxidative stress & anti-oxidative activity

Research Highlights: Fatigue is a frequent symptom in both healthy individuals and patients, therefore, biomarkers indicating several differential levels of fatigue would be needed for evaluating fatigue and its improvement. Following the hard work term, the mean values of oxidative … Continue reading

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The many roads to mitochondrial dysfunction in neuroimmune & neuropsychiatric disorders

Research abstract: BACKGROUND Mitochondrial dysfunction and defects in oxidative metabolism are a characteristic feature of many chronic illnesses not currently classified as mitochondrial diseases. Examples of such illnesses include bipolar disorder, multiple sclerosis, Parkinson’s disease, schizophrenia, depression, autism, and chronic … Continue reading

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Dysfunctional energy metabolism and oxidative stress pathways in CFS

Research abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating long-term multisystem disorder with a central and inexplicably persistent fatigue symptom that is unable to be relieved by rest. Energy metabolism and oxidative stress have been recent focal points of … Continue reading

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