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Monthly Archives: October 2013
Possible causes of mitochondrial dysfunctions in ME
Abstract Myalgic encephalomyelitis / chronic fatigue syndrome (ME/cfs) is classified by the World Health Organization as a disorder of the central nervous system. ME/cfs is an neuro-immune disorder accompanied by chronic low-grade inflammation, increased levels of oxidative and nitrosative stress … Continue reading
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Tagged Gerwyn Morris, immuno-flammatory pathway, Michael Maes, mitochondrial dysfunction, nitrosative stress, oxidative stress
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Cytokines and CFS
Abstract A major hypothesis for the cause of chronic fatigue syndrome (CFS) is immune dysregulation, thought to reflect upregulated pro-inflammatory cytokines leading to the symptoms characteristic of this illness. Because symptoms worsen with physical exertion or sleep loss, we hypothesized … Continue reading
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Tagged immune dysregulation, PBLs, peripheral blood lymphocytes, pro-inflammatory cytokines
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Fatigue in cancer and CFS
Abstract BACKGROUND Androgen deprivation therapy (ADT) often worsens fatigue in patients with prostate cancer, producing symptoms similar to chronic fatigue syndrome (CFS). Comparing expression (mRNA) of many fatigue-related genes in patients with ADT-treated prostate cancer versus with CFS versus healthy … Continue reading
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Tagged ADT, Androgen deprivation therapy, cancer, DBI, fatigue, GABA-A receptor modulator, gene expression
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Information processing problems in CFS
Research abstract Information processing difficulties are common in patients with chronic fatigue syndrome (CFS). It has been shown that the time it takes to process a complex cognitive task, rather than error rate, may be the critical variable underlying CFS … Continue reading
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Tagged ANT, Attention Network Task, cognitive dysfunction, Dr Benjamin Natelsen, Dr Gudrun Lange, Fumiharu Togo, information processing, Karen S Quigley
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Young People’s assembly – have your say
There is still time to tell Funky Dragon, the children and young people’s assembly for Wales, what you think they should be doing in 2013/14. Their mission is to enable children and young people up to aged 25 in Wales to … Continue reading
Which symptom would you most want health professionals in Wales to help you with?
Email us if you chose option 9, or have any comments on this poll.
No evidence that cervical cancer vaccine causes CFS
The Medicines and Healthcare products Regulatory Agency (MHRA) has found no evidence that Cervarix – an HPV vaccine which protects against cervical cancer- causes chronic fatigue syndrome, also known as ME. The MHRA’s scientists conducted their study after reports that … Continue reading
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Brain fog in POTS
Research abstract PURPOSE: Adolescents with postural tachycardia syndrome (POTS) often experience ill-defined cognitive impairment referred to by patients as ‘‘brain fog.’’ The objective of this study was to evaluate the symptom of brain fog as a means of gaining further … Continue reading
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Tagged Amanda J Ross, brain fog, cognition, orthostatic intolerance, postural tachycardia syndrome, POTS
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Post-exertion malaise in CFS: symptoms & gene expression
Research abstract BACKGROUND A primary complaint of chronic fatigue syndrome (CFS) patients is post-exertion malaise, which is a worsening of symptoms following activities such as exercise. PURPOSE To examine the link between gene expression for metabolite, adrenergic, immune, and glucocorticoid … Continue reading
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Tagged Alan R Light, gene expression, glucocorticoid sensitivity, Jacob D Meyer, PEM, Post-exertional malaise
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BackCare Awareness Week, Oct 7th-11th 2013
This year’s campaign is ‘Caring for Carers’. Carers provide invaluable help and assistance to their children, friends, relatives, and partners, but what happens when their work leads to back pain, compromising their ability to care? Back pain is endemic among … Continue reading
