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ME/CFS patients exhibit altered T cell metabolism & cytokine associations
Myalgic encephalomyelitis/chronic fatigue syndrome patients exhibit altered T cell metabolism and cytokine associations, by Alexandra H Mandarano, Jessica Maya, Ludovic Giloteaux, Daniel L Peterson, Marco Maynard, C Gunnar Gottschalk, and Maureen R Hanson in J Clin Invest. 2019. [First published … Continue reading
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Tagged Alexandra H Mandarano, CD8+ T cells, Dr Daniel Peterson, glycolysis, Gunnar Gottschalk, Jessica Maya, Ludovic Giloteaux, Marco Maynard, Prof Maureen Hanson, T cell activation
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Cellular bioenergetics is impaired in patients with CFS
Research abstract: Cellular bioenergetics is impaired in patients with chronic fatigue syndrome, by Cara Tomas, Audrey Brown, Victoria Strassheim, Joanna Elson, Julia Newton, Philip Manning in PLOSone [Published: October 24, 2017] Chronic fatigue syndrome (CFS) is a highly debilitating disease of … Continue reading
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Tagged Audrey Brown, bioenergetics, Cara Thomas, Dr Joanna Elson, glycolysis, oxidative phosphorylation, OXPHOS, PBMC, peripheral blood mononuclear cells, Philip Manning, Prof Julia Newton, Victoria Strassheim
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Elevated energy production by non-mitochondrial sources in CFS sub-group
Research abstract: Chronic Fatigue Syndrome (CFS) is a debilitating disease characterized by physical and mental exhaustion. The underlying pathogenesis is unknown, but impairments in certain mitochondrial functions have been found in some CFS patients. To thoroughly reveal mitochondrial deficiencies in … Continue reading
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Tagged ATP, Chung-Han Hsieh, Dana March, glycolysis, mitochondrial dysfunction, Nick Lawson, sub-groups, Xinnan Wang
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