Tag Archives: PBMC

Unravelling ME/CFS: Gender‐specific changes in the microRNA expression profiling in ME/CFS

Unravelling ME/CFS: Gender‐specific changes in the microRNA expression profiling in ME/CFS by Amanpreet K Cheema, Leonor Sarria, Mina Bekheit, Fanny Collado, Eloy Almenar‐Pérez, Eva Martín‐Martínez, Jose Alegre, Jesus Castro‐Marrero, Mary A Fletcher, Nancy G Klimas,  Elisa Oltra, Lubov Nathanson in … Continue reading

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The effect of ME/CFS severity on cellular bioenergetic function

The effect of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) severity on cellular bioenergetic function, by Cara Tomas, Joanna L Elson, Victoria Strassheim, Julia L Newton, Mark Walker in PLoS One vol 15, #4, e0231136, April 10, 2020   Research abstract: Myalgic … Continue reading

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Cytomegalovirus, Epstein‐Barr virus, & human herpesvirus‐6 infections in patients with ME/CFS (Bulgaria)

Cytomegalovirus, Epstein‐Barr Virus and Human Herpesvirus 6 infections in patients with Myalgic Еncephalomyelitis/Chronic Fatigue Syndrome, by Evelina Shikova, Valentina Reshkova, Аntoniya Kumanova, Sevdalina Raleva,Dora Alexandrova, Natasa Capo, Modra Murovska ( on behalf of the European Network on ME/CFS (EUROMENE) in … Continue reading

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Assessing diagnostic value of microRNAs from peripheral blood mononuclear cells & extracellular vesicles in ME/CFS

Assessing diagnostic value of microRNAs from peripheral blood mononuclear cells and extracellular vesicles in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome by Eloy Almenar-Pérez, Leonor Sarría, Lubov Nathanson & Elisa Oltra in Scientific Reports vol 10, no: 2064 (2020)   Research abstract: Myalgic … Continue reading

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An investigation into the modulation of T cell phenotypes by amitriptyline & nortriptyline

An investigation into the modulation of T cell phenotypes by amitriptyline and nortriptyline, by JonathanRoyds, Melissa J Conroy, Margaret R Dunne, Connail McCrory, Joanne Lysaght in European Neuropsychopharmacology, Dec 2019[doi.org/10.1016/j.euroneuro.2019.12.106]   Research abstract: Amitriptyline is prescribed for treating the symptoms … Continue reading

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Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test

Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test, by Cara Tomas, Tiffany A Lodge, Michelle Potter, Joanna L Elson, Julia L Newton, Karl J Morten, in Sci Rep. 2019 Aug 7;9(1):11464. doi: 10.1038/s41598-019-47966-z.   Research abstract: The … Continue reading

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Cellular bioenergetics is impaired in patients with CFS

Research abstract: Cellular bioenergetics is impaired in patients with chronic fatigue syndrome, by Cara Tomas, Audrey Brown, Victoria Strassheim, Joanna Elson, Julia Newton, Philip Manning in PLOSone [Published: October 24, 2017] Chronic fatigue syndrome (CFS) is a highly debilitating disease of … Continue reading

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MEA to fund new research into biomarkers and markers of disease activity in people with severe ME/CFS

ME Association announcement, 20 December 2016: MEA to fund new research into biomarkers and markers of disease activity in people with severe ME/CFS We are pleased to announce that – following the normal rigorous peer review procedures – the MEA Ramsay … Continue reading

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Mast cell dysfunction in ME/CFS

Research abstract: BACKGROUND: Mast cells (MCs) mediate inflammation through neuropeptides and cytokines, along with histamine and reactive oxygen species (ROS). Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is an illness characterized by an unexplained disabling fatigue with multiple physiological impairments as well as … Continue reading

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