Tag Archives: peripheral blood mononuclear cells

Recursive ensemble feature selection provides a robust mRNA expression signature for ME/CFS

Recursive ensemble feature selection provides a robust mRNA expression signature for myalgic encephalomyelitis/chronic fatigue syndrome, by Paula I Metselaar, Lucero Mendoza-Maldonado, Andrew Yung Fong Li Yim, Ilias Abarkan, Peter Henneman, Anje A Te Velde, Alexander Schönhuth, Jos A Bosch, Aletta … Continue reading

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Impact of long-term cryopreservation on blood immune cell markers in ME/CFS: implications for biomarker discovery

Impact of long-term cryopreservation on blood immune cell markers in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: implications for biomarker discovery, by Elisabet Gómez-Mora,  Jorge Carrillo,  Víctor Urrea,  Josepa Rigau,  José Alegre,  Cecilia Cabrera,  Elisa Oltra,  Jesús Castro-Marrero and  Julià Blanco in Front. … Continue reading

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Changes in DNA methylation profiles of ME/CFS patients reflect systemic dysfunctions

Changes in DNA methylation profiles of myalgic encephalomyelitis/chronic fatigue syndrome patients reflect systemic dysfunctions, by AM Helliwell, EC Sweetman, PA Stockwell, CD Edgar, A Chatterjee & WP Tate in Clinical Epigenetics vol 12, no: 167 (2020)   Research abstract: Background: … Continue reading

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A SWATH-MS analysis of ME/CFS peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction

A SWATH-MS analysis of ME/CFS peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction, by Eiren Sweetman, Torsten Kleffmann, Christina Edgar, Michel de Lange, Rosamund Vallings & Warren Tate in Journal of Translational Medicine vol 18, no: 365 (2020) [doi.org/10.1186/s12967-020-02533-3]   Research … Continue reading

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Unravelling ME/CFS: Gender‐specific changes in the microRNA expression profiling in ME/CFS

Unravelling ME/CFS: Gender‐specific changes in the microRNA expression profiling in ME/CFS by Amanpreet K Cheema, Leonor Sarria, Mina Bekheit, Fanny Collado, Eloy Almenar‐Pérez, Eva Martín‐Martínez, Jose Alegre, Jesus Castro‐Marrero, Mary A Fletcher, Nancy G Klimas,  Elisa Oltra, Lubov Nathanson in … Continue reading

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The effect of ME/CFS severity on cellular bioenergetic function

The effect of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) severity on cellular bioenergetic function, by Cara Tomas, Joanna L Elson, Victoria Strassheim, Julia L Newton, Mark Walker in PLoS One vol 15, #4, e0231136, April 10, 2020   Research abstract: Myalgic … Continue reading

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Assessing diagnostic value of microRNAs from peripheral blood mononuclear cells & extracellular vesicles in ME/CFS

Assessing diagnostic value of microRNAs from peripheral blood mononuclear cells and extracellular vesicles in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome by Eloy Almenar-Pérez, Leonor Sarría, Lubov Nathanson & Elisa Oltra in Scientific Reports vol 10, no: 2064 (2020)   Research abstract: Myalgic … Continue reading

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An investigation into the modulation of T cell phenotypes by amitriptyline & nortriptyline

An investigation into the modulation of T cell phenotypes by amitriptyline and nortriptyline, by JonathanRoyds, Melissa J Conroy, Margaret R Dunne, Connail McCrory, Joanne Lysaght in European Neuropsychopharmacology, Dec 2019[doi.org/10.1016/j.euroneuro.2019.12.106]   Research abstract: Amitriptyline is prescribed for treating the symptoms … Continue reading

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Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test

Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test, by Cara Tomas, Tiffany A Lodge, Michelle Potter, Joanna L Elson, Julia L Newton, Karl J Morten, in Sci Rep. 2019 Aug 7;9(1):11464. doi: 10.1038/s41598-019-47966-z.   Research abstract: The … Continue reading

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Mitochondrial complex activity in permeabilised cells of CFS patients using two cell types

Mitochondrial complex activity in permeabilised cells of CFS patients using two cell types, by Cara Tomas, Audrey E Brown, Julia L Newton and Joanna L Elson in Peer Journal, 1 Mar 2019   Article abstract: Abnormalities in mitochondrial function have … Continue reading

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