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The effect of ME/CFS severity on cellular bioenergetic function
The effect of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) severity on cellular bioenergetic function, by Cara Tomas, Joanna L Elson, Victoria Strassheim, Julia L Newton, Mark Walker in PLoS One vol 15, #4, e0231136, April 10, 2020 Research abstract: Myalgic … Continue reading
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Tagged bioenergetics, Cara Tomas, Dr Joanna Elson, glycolytic function, Mark Walker, mitochondrial dysfunction, PBMC, peripheral blood mononuclear cells, Prof Julia Newton, respiratory acidification, Victoria Strassheim
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The role of mitochondria in ME/CFS: a perspective
The role of mitochondria in ME/CFS: a perspective, by Cara Tomas, Joanna L Elson in Fatigue: Biomedicine, Health & Behavior, 26 Feb 2019 Research review abstract: Chronic fatigue syndrome (CFS) also known as Myalgic encephalomyelitis (ME) is a debilitating … Continue reading
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Tagged bioenergetics, Cara Tomas, Dr Joanna Elson, mitochondrial DNA
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Cellular bioenergetics is impaired in patients with CFS
Research abstract: Cellular bioenergetics is impaired in patients with chronic fatigue syndrome, by Cara Tomas, Audrey Brown, Victoria Strassheim, Joanna Elson, Julia Newton, Philip Manning in PLOSone [Published: October 24, 2017] Chronic fatigue syndrome (CFS) is a highly debilitating disease of … Continue reading
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Tagged Audrey Brown, bioenergetics, Cara Thomas, Dr Joanna Elson, glycolysis, oxidative phosphorylation, OXPHOS, PBMC, peripheral blood mononuclear cells, Philip Manning, Prof Julia Newton, Victoria Strassheim
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A new approach for investigating mitochondrial DNA in ME
Research abstract: In mitochondrial research, many investigators have examined the association between mitochondrial DNA (mtDNA) variants in rare as well as common complex diseases. Previous studies at the CHM (NWU) detected three known pathogenic mtDNA variants (m.7497G>A, m.9185T>C and m.10197G>A) at … Continue reading
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Tagged bioenergetics, haplogroups, mitochondrial dysfunction, mtDNA, Seahorse XF analyser
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