Author Archives: wames

Hypothalamic-Pituitary-Adrenal Hypofunction in ME/CFS

Posted on 11/09/2016 by wames

Review abstract: There is evidence that immune-inflammatory and oxidative and nitrosative stress (O&NS) pathways play a role in the pathophysiology of myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS). There is also evidence that these neuroimmune diseases are accompanied by hypothalamic-pituitary-adrenal (HPA) axis … Continue reading →

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Studies on CBT & GET for ME/CFS are misleading, says Swedish prof

Posted on 11/09/2016 by wames

Article abstract: There have been a number of studies on Cognitive Behavioral Therapy (CBT) and Graded Exercise Therapy (GET) for ME/CFS based on a treatment model where the disease is perpetuated by cognitive processes. Although the studies are flawed and … Continue reading →

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Dr Keith Geraghty requests experiences of CBT & GET

Posted on 11/08/2016 by wames

Dr Keith Geraghty, researcher at the University of Manchester (@keithgeraghty) has tweeted at 6:09 p.m. on Mon, Nov 07, 2016: Ever experience adverse reactions to CBT or GET in CFS treatment – email me @ Keith.geraghty@manchester.ac.uk – we want to hear … Continue reading →

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Activity patterns in response to symptoms in patients being treated for CFS

Posted on 11/07/2016 by wames

Research abstract: Objective: Cognitive-behavioral models of chronic fatigue syndrome (CFS) propose that patients respond to symptoms with 2 predominant activity patterns-activity limitation and all-or-nothing behaviors-both of which may contribute to illness persistence. The current study investigated whether activity patterns occurred at the same time … Continue reading →

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Postexertion ‘crash,’ not fatigue per se, marks CFS

Posted on 11/07/2016 by wames

Medscape Medical News article, by Miriam Tucker, November 04, 2016: Post exertion ‘Crash,’ not Fatigue per se, Marks Syndrome Article extract: The name “chronic fatigue syndrome” is being phased out not just because it is viewed as trivializing a condition that renders … Continue reading →

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PACE-gate: when clinical trial evidence meets open data access

Posted on 11/07/2016 by wames

Article abstract: Science is not always plain sailing and sometimes the voyage is across an angry sea. A recent clinical trial of treatments for chronic fatigue syndrome (the PACE trial) has whipped up a storm of controversy. Patients claim the … Continue reading →

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The most extreme consequence of ME/CFS – trauma & premature death

Posted on 11/04/2016 by wames

Livets bilder (Life images) blog post, 25 October 2016: The most extreme consequence – trauma and premature death  (Originally written in Swedish) In this post I will write about something that I see as the most extreme consequence of what I … Continue reading →

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ME researchers identify danger of contamination in ME/CFS genomics study

Posted on 11/04/2016 by wames

Research abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating disease causing indefinite fatigue. ME/CFS has long been hypothesised to have an infectious cause; however, no specific infectious agent has been identified. We used metagenomics to analyse the RNA from … Continue reading →

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Which countries conduct ME/CFS research?

Posted on 11/03/2016 by wames

Phoenix rising forum post, by HIP, January 2016: Why so little ME/CFS research from France and Germany? There seems to be little ME/CFS research done in France and Germany, relative to their overall scientific output. Why is this? Using a … Continue reading →

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FITNET trial reporting is misleading

Posted on 11/03/2016 by wames

Major charities and individuals have joined WAMES in expressing concern about the nature of the FITNET trial being run by Prof Esther Crawley, the lack of objective analysis in the media coverage and the questionable results from the original Dutch trial. WAMES does … Continue reading →

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