Author Archives: wames

Central sensitization: a pathogenic mechanism in complex undefined diseases

Central sensitization: A pathogenic mechanism in complex undefined diseases, by Joaquim Fernández-Solà, in Neuropsychiatry (London) 2019: 9(6), 2485–2490   Abstract: There is a common perception that complex undefined diseases manifested with diverse combination of symptoms and a difficult clinical diagnosis have … Continue reading

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An investigation into the modulation of T cell phenotypes by amitriptyline & nortriptyline

An investigation into the modulation of T cell phenotypes by amitriptyline and nortriptyline, by JonathanRoyds, Melissa J Conroy, Margaret R Dunne, Connail McCrory, Joanne Lysaght in European Neuropsychopharmacology, Dec 2019[doi.org/10.1016/j.euroneuro.2019.12.106]   Research abstract: Amitriptyline is prescribed for treating the symptoms … Continue reading

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Register your interest today in taking part in ME/CFS genome-wide research!

The ME/CFS Biomedical Partnership Genome-wide association study The ME/CFS Biomedical Partnership is working on a funding application to be made in early 2020 to the MRC/NIHR for a genome-wide association study.   How can we help? They need to demonstrate … Continue reading

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WAMES helpline holiday hours 2019-2020

WAMES helpline hours The WAMES helpline is run by volunteers and will be closed over the festive period.   We apologise that due to extra pressures on the team in January, the closure will last longer than usual. Feel free … Continue reading

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Minireview for CFS & its medical attention recently

Minireview for Chronic Fatigue Syndrome and its medical attention recently, by Chang-Gue Son in J Korean Med. 2019;40(4):84-90 [http://dx.doi.org/10.13048/jkm.19043]   Review abstract: Objectives: Chronic fatigue syndrome (CFS) is a debilitating illness impairing seriously quality of life, while CFS would be … Continue reading

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Transient receptor potential melastatin 2 channels are overexpressed in ME/CFS patients

Transient receptor potential melastatin 2 channels are overexpressed in myalgic encephalomyelitis/chronic fatigue syndrome patients, by Cassandra Balinas, Helene Cabanas, Donald Staines, Sonya Marshall-Gradisnik in Journal of Translational Medicine Vol 17, #1, p 401, December 3, 2019   Research abstract: Background: Myalgic … Continue reading

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Paediatric CFS patients’ & parents’ perceptions of recovery

Paediatric chronic fatigue syndrome patients’ and parents’ perceptions of recovery, by Matthew Robert Harland, Roxanne Morin Parslow, Nina Anderson, Danielle Byrne, Esther Crawley in BMJ Paediatrics Open Vol 3, #1, Dec 2, 2019   Research abstract: What is known about the … Continue reading

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A laboratory approach for characterizing chronic fatigue: what does metabolomics tell us?

A laboratory approach for characterizing chronic fatigue: What does metabolomics tell us? by Elardus Erasmus, Shayne Mason, Mari van Reenen, Francois E Steffens, B Chris Vorster, Carolus J Reinecke in Metabolomics Vol 15, p 158, November 27, 2019   Research … Continue reading

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Elevated blood lactate in resting conditions correlate with post-exertional malaise severity in patients with ME/CFS

Elevated blood lactate in resting conditions correlate with post-exertional malaise severity in patients with Myalgic encephalomyelitis/Chronic fatigue syndrome by Alaa Ghali, Carole Lacout, Maria Ghali, Aline Gury, Anne-Berengere Beucher, Pierre Lozac’h, Christian Lavigne & Geoffrey Urbanski (France) in Nature Scientific … Continue reading

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ME/CFS patients exhibit altered T cell metabolism & cytokine associations

Myalgic encephalomyelitis/chronic fatigue syndrome patients exhibit altered T cell metabolism and cytokine associations, by Alexandra H Mandarano, Jessica Maya, Ludovic Giloteaux, Daniel L Peterson, Marco Maynard, C Gunnar Gottschalk, and Maureen R Hanson in J Clin Invest. 2019. [First published … Continue reading

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