Author Archives: wames
Central sensitization: a pathogenic mechanism in complex undefined diseases
Central sensitization: A pathogenic mechanism in complex undefined diseases, by Joaquim Fernández-Solà, in Neuropsychiatry (London) 2019: 9(6), 2485–2490 Abstract: There is a common perception that complex undefined diseases manifested with diverse combination of symptoms and a difficult clinical diagnosis have … Continue reading
An investigation into the modulation of T cell phenotypes by amitriptyline & nortriptyline
An investigation into the modulation of T cell phenotypes by amitriptyline and nortriptyline, by JonathanRoyds, Melissa J Conroy, Margaret R Dunne, Connail McCrory, Joanne Lysaght in European Neuropsychopharmacology, Dec 2019[doi.org/10.1016/j.euroneuro.2019.12.106] Research abstract: Amitriptyline is prescribed for treating the symptoms … Continue reading
Register your interest today in taking part in ME/CFS genome-wide research!
The ME/CFS Biomedical Partnership Genome-wide association study The ME/CFS Biomedical Partnership is working on a funding application to be made in early 2020 to the MRC/NIHR for a genome-wide association study. How can we help? They need to demonstrate … Continue reading
WAMES helpline holiday hours 2019-2020
WAMES helpline hours The WAMES helpline is run by volunteers and will be closed over the festive period. We apologise that due to extra pressures on the team in January, the closure will last longer than usual. Feel free … Continue reading
Minireview for CFS & its medical attention recently
Minireview for Chronic Fatigue Syndrome and its medical attention recently, by Chang-Gue Son in J Korean Med. 2019;40(4):84-90 [http://dx.doi.org/10.13048/jkm.19043] Review abstract: Objectives: Chronic fatigue syndrome (CFS) is a debilitating illness impairing seriously quality of life, while CFS would be … Continue reading
Transient receptor potential melastatin 2 channels are overexpressed in ME/CFS patients
Transient receptor potential melastatin 2 channels are overexpressed in myalgic encephalomyelitis/chronic fatigue syndrome patients, by Cassandra Balinas, Helene Cabanas, Donald Staines, Sonya Marshall-Gradisnik in Journal of Translational Medicine Vol 17, #1, p 401, December 3, 2019 Research abstract: Background: Myalgic … Continue reading
Paediatric CFS patients’ & parents’ perceptions of recovery
Paediatric chronic fatigue syndrome patients’ and parents’ perceptions of recovery, by Matthew Robert Harland, Roxanne Morin Parslow, Nina Anderson, Danielle Byrne, Esther Crawley in BMJ Paediatrics Open Vol 3, #1, Dec 2, 2019 Research abstract: What is known about the … Continue reading
Elevated blood lactate in resting conditions correlate with post-exertional malaise severity in patients with ME/CFS
Elevated blood lactate in resting conditions correlate with post-exertional malaise severity in patients with Myalgic encephalomyelitis/Chronic fatigue syndrome by Alaa Ghali, Carole Lacout, Maria Ghali, Aline Gury, Anne-Berengere Beucher, Pierre Lozac’h, Christian Lavigne & Geoffrey Urbanski (France) in Nature Scientific … Continue reading
ME/CFS patients exhibit altered T cell metabolism & cytokine associations
Myalgic encephalomyelitis/chronic fatigue syndrome patients exhibit altered T cell metabolism and cytokine associations, by Alexandra H Mandarano, Jessica Maya, Ludovic Giloteaux, Daniel L Peterson, Marco Maynard, C Gunnar Gottschalk, and Maureen R Hanson in J Clin Invest. 2019. [First published … Continue reading