Category Archives: News

The effect of significant other responses on CFS symptom fluctuations

Research abstract: Objective: Significant other responses to patients’ symptoms are important for patient illness outcomes in chronic fatigue syndrome (CFS/ME); negative responses have been associated with increased patient depression, whilst increased disability and fatigue have been associated with solicitous significant other responses. The current … Continue reading

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The effect of subjective sleep on fatigue in CFS

Research abstract: Study Objectives: This study aimed to (1) examine the relationship between subjective and actigraphy-defined sleep, and next-day fatigue in chronic fatigue syndrome (CFS); and (2) investigate the potential mediating role of negative mood on this relationship. We also … Continue reading

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Dr David Maughan discusses ME, it’s treatment and it’s difficult politics

Researcher Dr. David Maughan of the University of Vermont, and Advocate Rik Carlson discuss the disease, it’s treatment, and the difficult politics surrounding this disease in particular, in the Paradigms blog: What is Myalgic Encephalomyelitis, also known as Chronic Fatigue … Continue reading

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Rethinking childhood adversity in CFS

Research abstract: Objectives: Previous studies have consistently shown increased rates of childhood adversity in chronic fatigue syndrome (CFS). However, such aetiopathogenic studies of CFS are potentially confounded by co-morbidity and misdiagnosis particularly with depression. We used a modelling approach with existing data and data … Continue reading

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Anti-citrullinated protein antibodies in CFS

The Vermont CFIDS Association reports on a recent pilot study and invites contributions to enable further research: While preliminary, the results from this University of Vermont study is the first evidence for the potential existence of autoantibodies in ME/CFS, indicative … Continue reading

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Junior doctors’ experiences of managing patients with MUS

Research abstract: Objectives:  To explore junior doctors’ knowledge about and experiences of managing patients with medically unexplained symptoms (MUS) and to seek their recommendations for improved future training on this important topic about which they currently receive little education. Design: … Continue reading

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CFS symptom profiles in UK & Netherlands

Research highlights: • We explore chronic fatigue syndrome (CFS) phenotypes in two large clinical cohorts. • Adults with CFS may have one of 6 symptom-based phenotypes. • Phenotypes were associated with sex, duration of illness, and comorbidity. • Polysymptomatic patients … Continue reading

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CFS/ME pathophysiology, diagnosis & treatment overview

Review abstract: The underlying pathophysiology in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is unclear, and there is disagreement in the field over diagnostic criteria and treatments. Here, we review the literature and comment on the debate around this condition. Chronic fatigue … Continue reading

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Interview with Dr Judy Mikovits: a medical whistleblower’s tale

Global Freedom Movement video interview: Drugs, Disease and Deception: A Medical Whistleblower’s Tale with Judy Mikovits Phd Meet Dr. Judy Mikovits, a passionate research molecular biologist and biochemist; wrongfully jailed with her career destroyed forever because she dared to publish … Continue reading

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Pregabalin has positive effect on FM symptoms

Research abstract: Pregabalin, an approved treatment for fibromyalgia (FM), has been shown to decrease sympathetic nervous system (SNS) activity and inhibit sympathetically maintained pain, but its effects on exercise responses have not been reported. Methods: Using a randomized double-blind crossover … Continue reading

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