Category Archives: News

COMT gene dysfunction linked to susceptibility to infection in CFS

Research abstract: BACKGROUND: Chronic fatigue syndrome (CFS) is considered as a neuroimmunological disease but the etiology and pathophysiology is poorly understood. Patients suffer from sustained exhaustion, cognitive impairment and an increased sensitivity to pain and sensory stimuli. A subset of … Continue reading

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Fluctuations in CFS symptoms affects ability to remember them reliably

An earlier study by these researchers concluded that time frame, symptom stability, and momentary severity appear to influence reliability in reporting ME/CFS symptoms. These factors must be taken into account, because “[a]ccurate and reliable assessment is a crucial first step … Continue reading

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Evaluation of the UK’s first NHS generic fatigue clinic

Research abstract: Importance: Fatigue is a significant and debilitating symptom affecting 25% of the population. It occurs in those with a range of chronic diseases, can be idiopathic and in 0.2–0.4% of the UK population occurs in combination with other … Continue reading

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Childhood trauma did not increase changes to DNA in women with CFS

Research abstract: OBJECTIVES: Chronic fatigue syndrome (CFS) has been associated with hypothalamic-pituitary-adrenal axis hypofunction and enhanced glucocorticoid receptor (GR) sensitivity. In addition, childhood trauma is considered a major risk factor for the syndrome. This study examines DNA methylation of the … Continue reading

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Are ME and CFS different illnesses?

Research abstract Considerable discussion has transpired regarding whether chronic fatigue syndrome is a distinct illness from Myalgic Encephalomyelitis. A prior study contrasted the Myalgic Encephalomyelitis International Consensus Criteria (ME-ICC; Carruthers et al., 2011) with the Fukuda et al. (1994) CFS … Continue reading

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The impact of CFS on cognitive functioning in adolescents

Research abstract: Chronic fatigue syndrome (CFS) is characterized by persistent fatigue and severe disability. Most adolescent patients report attention and concentration problems, with subsequent poor performance at school. This study investigated the impact of CFS on intellectual capacity by (1) … Continue reading

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Anti-neural antibody response in Lyme v ME/CFS

No research abstract available: Anti-neural antibody response in patients with post- treatment Lyme disease symptoms versus those with myalgic encephalomyelitis/chronic fatigue syndrome, by Ajamian M, Cooperstock M, Wormser GP, Vernon SD, Alaedini A. in Brain Behav Immun. 2015 Aug;48:354-5.

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Mitoprotective dietary approaches for ME/CFS

Research abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome is an idiopathic illness characterized by debilitating fatigue and neuro-immune abnormalities. A growing body of evidence proposes mitochondrial dysfunction as a central perpetrator of the illness due to activation of immune-inflammatory pathways that burden … Continue reading

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The many roads to mitochondrial dysfunction in neuroimmune & neuropsychiatric disorders

Research abstract: BACKGROUND Mitochondrial dysfunction and defects in oxidative metabolism are a characteristic feature of many chronic illnesses not currently classified as mitochondrial diseases. Examples of such illnesses include bipolar disorder, multiple sclerosis, Parkinson’s disease, schizophrenia, depression, autism, and chronic … Continue reading

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Multidisciplinary rehabilitation treatment versus CBT for patients with CFS

Abstract OBJECTIVES: The aim of this trial was to evaluate the difference in treatment effect, at 26 and 52 weeks after the start of treatment, between cognitive behavioural therapy (CBT) and multidisciplinary rehabilitation treatment (MRT) for patients with chronic fatigue … Continue reading

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