Category Archives: News

Humoral immune dysfunction common in CFS

Research abstract: Chronic fatigue syndrome (CFS) is a severe disease characterized by various symptoms of immune dysfunction. CFS onset is typically with an infection and many patients suffer from frequently recurrent viral or bacterial infections. Immunoglobulin and mannose binding lectin … Continue reading

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TMD in CFS is indicator of greater autonomic dysfunction

Research abstract: Background: Chronic fatigue syndrome (CFS) is heterogeneous in nature, yet no clear subclassifications currently exist. There is evidence of dysautonomia in almost 90% of patients and CFS is often co-morbid with conditions associated with autonomic nervous system (ANS) dysfunction,  such as … Continue reading

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Can Mindfulness reduce stress in long term physical conditions?

Review abstract: OBJECTIVE: To identify whether mindfulness-based stress reduction is effective in improving physical health outcomes for long-term physical conditions. METHOD: A systematic review of the literature (retrieved from MEDLINE, PubMed and PsycINFO). RESULTS: Fifteen studies were included in the … Continue reading

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Dysfunctional pain – challenges for drug discovery

Research abstract: ‘Dysfunctional pain’, a type of chronic pain, is associated with a broad range of clinical disorders, including fibromyalgia, irritable bowel syndrome and interstitial cystitis. It is emerging as a serious issue due to the negative impact of inexplicable … Continue reading

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Association between cognitive performance & pain in CFS

Research abstract: BACKGROUND: In addition to the frequently reported pain complaints, performance-based cognitive capabilities in patients with chronic fatigue syndrome (CFS) with and without comorbid fibromyalgia (FM) are significantly worse than those of healthy controls. In various chronic pain populations, … Continue reading

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Do people with ME and CFS really recover?

The Recovery Question, by Dan Neuffer in Health Rising Forum, Sep 17 2015 There is much information out there on how to diagnose Fibromyalgia Syndrome (FMS) or Chronic Fatigue Syndrome (CFS) (also described as Myalgic Encephalomyelitis or ME). And whilst … Continue reading

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Perfectionism & stress in CFS could be due to HPA dysregulation

Article Background: There is increasing evidence that Chronic Fatigue Syndrome (CFS) may reflect a dysregulation of the hypothalamic–pituitary–adrenal (HPA) axis after a prolonged period of hyperactivity due to chronic stress/overload. We and others have hypothesized that chronic stress and subsequent … Continue reading

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Oxidative phosphorylation & lactic acid excretion are impaired in severe ME

Case study abstract: Background: In this study the muscle bioenergetic function in response to exercise in severe ME was explored to see if the underlying metabolic problem in ME, responsible for the severe difficulties with trivial exercise, and the severe loss … Continue reading

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Key issues for understanding ME, biological markers & diagnostic criteria

Review abstract: Myalgic Encephalomyelitis (ME) continues to cause significant morbidity worldwide with an estimated one million cases in the United States. Hurdles to establishing consensus to achieve accurate evaluation of patients with ME continue, fuelled by poor agreement about case definitions, … Continue reading

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Group CBT for CFS

Research abstract: BACKGROUND: Meta-analyses have been inconclusive about the efficacy of cognitive behaviour therapies (CBTs) delivered in groups of patients with chronic fatigue syndrome (CFS) due to a lack of adequate studies. METHODS: We conducted a pragmatic randomised controlled trial … Continue reading

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