Category Archives: News
Brain-derived neurotrophic factor concentration may not be depressed in CFS
Research abstract: Due to its effect on the central nervous system, brain-derived neurotrophic factor (BDNF) has been hypothesized to be involved in a number of neurodegenerative and psychiatric disorders. Recently, BDNF was also reported to be significantly lower in patients … Continue reading
Computer simulation explores cause for exercise intolerance in ME/CFS
Research abstract: Post-exertional malaise is commonly observed in patients with myalgic encephalomyelitis/chronic fatigue syndrome, but its mechanism is not yet well understood. A reduced capacity for mitochondrial ATP synthesis is associated with the pathogenesis of CFS and is suspected to … Continue reading
Inflammatory hypothesis of mood spectrum
Review abstract OBJECTIVES: The present paper aimed at reviewing literature data on the inflammatory hypothesis of mood spectrum, as well as the overlapping features with some chronic rheumatologic disorders, in particular fibromyalgia and chronic fatigue syndrome. METHODS: A literature search … Continue reading
Autoimmune/inflammatory syndrome induced by adjuvants
Research abstract: In 1964, Miyoshi reported a series of patients with diverse symptoms after receiving treatment with silicone or paraffin fillers. Miyoshi named this condition ‘human adjuvant disease’. Since then, the literature has been flooded with case reports and case … Continue reading
Review of exercise therapy studies
Review abstract BACKGROUND: Chronic fatigue syndrome (CFS) is characterised by persistent, medically unexplained fatigue, as well as symptoms such as musculoskeletal pain, sleep disturbance, headaches and impaired concentration and short-term memory. CFS presents as a common, debilitating and serious health … Continue reading
Immune biomarkers discussion
A team of American scientists discuss Prof Mady Hornig’s recent research on immune signatures in ME/CFS. They review identification of immune biomarkers in CFS/ME patients, and how a cell nuclease controls the innate immune response to vaccinia virus infection. [Introductions last about … Continue reading
Appropriate management of FM & CFS can give moderate improvements
Research abstract: Fibromyalgia and chronic fatigue syndrome represent two of the most commonly encountered functional somatic syndromes in clinical practice. Both have been contentious diagnoses in the past, and this diagnostic dispute has resulted in a therapeutic nihilism that has … Continue reading
Sleep/wake behaviour in ME/CFS
Research abstract: Sleep dysfunction is a prominent feature in the subjective experience of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Although studies using polysomonography have identified at least one abnormal sleep characteristic in individuals with ME/CFS, no standard abnormalities in sleep have … Continue reading
Why exercise magnifies exhaustion in CFS
Study shows why exercise magnifies exhaustion for chronic fatigue syndrome patients [March 12 2015] The mechanism that causes high-performance athletes to “feel the burn” turns out to be the culprit in what makes people with chronic fatigue syndrome feel exhausted by … Continue reading
