Category Archives: News

The role of the HPA-axis in adolescent CFS

Abstract BACKGROUND: There is accumulating evidence of hypothalamic-pituitary-adrenal (HPA) axis hypofunction in chronic fatigue syndrome (CFS). However, knowledge of this hypofunction has so far come exclusively from research in adulthood, and its clinical significance remains unclear. The objective of the … Continue reading

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Immune dysregulation in CFS similar to autoimmune disorders

Abstract Perturbations in immune processes are a hallmark of a number of autoimmune and inflammatory disorders. Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is an inflammatory disorder with possible autoimmune correlates, characterized by reduced NK cell activity, elevations in regulatory T cells … Continue reading

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Immune dysfunction worse in severe CFS patients

Abstract Objective: Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a disabling illness, characterized by persistent, debilitating fatigue and a multitude of symptoms. Immunological alterations are prominent in CFS/ME cases, however little is known about the relationship between CFS/ME severity and the … Continue reading

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Adverse effects of antidepressants greater than reported

Abstract Background In the context of rapidly increasing antidepressant (AD) use internationally, and recent reviews raising concerns about efficacy and adverse effects, this study aimed to survey the largest sample of AD recipients to date. Methods An online questionnaire about … Continue reading

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Exercise intolerance in CFS caused by low oxygen extraction

Abstract Background: The insufficient metabolic adaptation to exercise in Chronic Fatigue Syndrome (CFS) is still being debated and poorly understood. Methods: We analysed the cardiopulmonary exercise tests of CFS patients, idiopathic chronic fatigue (CFI) patients and healthy visitors. Continuous non-invasive … Continue reading

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Medications cause 70% of dry eyes, mouth etc. in CFS

Chronic fatigue syndrome (CFS) is a heterogeneous and multisystemic disorder of unknown pathogenesis and etiology. It is characterized by prolonged generalized and abnormal fatigue post-exercise (98%), recurrent headache (90%) and problems of concentration and memory (85%) that have lasted for … Continue reading

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Cognitive dysfunction causes fatigue and depression in ME/CFS

Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by persistent emotional, mental, and physical fatigue accompanied by a range of neurological, autonomic, neuroendocrine, immune, and sleep problems. Research has shown that psychosocial factors such as anxiety and depression as … Continue reading

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Important to distinguish ME (with Post-exertional malaise) from CFS

Abstract Myalgic Encephalomyelitis (ME) was identified as a new clinical entity in 1959 and has been acknowledged as a disease of the central nervous system/neurological disease by the World Health Organisation since 1969. Cognitive impairment, (muscle) weakness, circulatory disturbances, marked … Continue reading

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Videos by ME experts online

Dutch patient group ME/cvs Vereniging has hosted 30+ 3-10 minute talks about various aspects of ME on their Youtube page. Speakers include: Dr Nigel Speight (WAMES advisor); Prof Dr Kenny Meirleir; Prof Dr FC Visser; Dr Meinte Vollema, Dr Charles … Continue reading

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Could you be the WAMES secretary?

The WAMES secretary’s post will become vacant at the April AGM. This post is critical for the smooth running of WAMES, an organisation which works to improve services and provide a better quality of life for people with ME in … Continue reading

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