Tag Archives: HHV-6

ME/CFS as a hyper-regulated immune system driven by an interplay between regulatory T cells & chronic human herpesvirus infections

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome as a hyper-regulated immune system driven by an interplay between regulatory T cells and chronic human herpesvirus infections, by Nuno Sepúlveda,  Jorge Carneiro,  Eliana M Lacerda and  Luis C Nacul in Front. Immunol. 21 Nov 2019 … Continue reading

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Human herpesvirus 6 and 7 are biomarkers for fatigue

Research highlights: Salivary HHV-6 and HHV-7 can be used for assessment of physiological fatigue. Activation and differentiation of macrophages are needed for viral reactivation. Salivary HHV-6 and HHV-7 do not increase with pathological fatigue. Salivary HHV-6/7 can distinguish between physiological … Continue reading

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Human herpesvirus 6 and the nervous system

Human herpesvirus (HHV)-6 is a β-herpesvirus that infects most infants by 2 years of age and persists in a variety of host cells after primary infection, with intermittent reactivation typically during periods of immunosuppression. HHV-6 has two closely related species, … Continue reading

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Valacyclovir (antiviral) treatment of chronic fatigue in adolescents

Abstract Chronic fatigue syndrome (CFS) presents with fatigue, low motivation, diminished mood, and reduced activity, all symptoms having extensive diagnostic overlaps with depression. Studies have linked chronic viral infections with CFS, and antiviral therapy has effectively treated CFS in adult … Continue reading

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Human herpesvirus-6 infection can be inherited

HHV-6 has been found in people with ME. Abstract Human herpesvirus-6 (HHV-6)A and 6B are ubiquitous betaherpesviruses viruses with lymphotropic and neurotropic potential. As reported earlier, these viruses establish latency by integration into the telomeres of host chromosomes. Chromosomally integrated … Continue reading

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Antiviral valganciclovir helps CFS subgroup

In a study by Dr Jose Montoya in the USA half of CFS patients suffering from HHV-6 and EBV viruses make an improvement of 30% or more. Abstract Valganciclovir has been reported to improve physical and cognitive symptoms in patients … Continue reading

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