Category Archives: News
Exercise testing and CFS
Abstract PURPOSE Cardiopulmonary exercise testing (CPET) is used to determine the etiology of unexplained exercise symptoms in otherwise healthy patients and those with well defined cardiopulmonary disease. Test results vary by baseline physical activity levels which are difficult to assess … Continue reading
Cytokines and neuropathic pain
Abstract Cytokines and chemokines are proteins that coordinate the immune response throughout the body. The dysregulation of cytokines and chemokines is a central feature in the development of neuroinflammation, neurodegeneration, and demyelination both in the central and peripheral nervous systems … Continue reading
Childhood stressors in the development of CFS and FM
Review Abstract Background Chronic fatigue syndrome (CFS) and fibromyalgia (FM) are both highly prevalent conditions associated with extreme disability and with the development of co-morbid psychiatric disorders, such as depression and anxiety. Childhood stressors have been shown to induce persistent … Continue reading
Functional capacity evaluation in CFS
Abstract Background: Objective measurements of function often form the basis for legal decisions about whether a patient is fit for return to work, or conversely, entitled to disability compensation. The functional capacity evaluation (FCE) is regarded as the gold standard for measuring work capacity … Continue reading
Accuracy of memory of CFS symptoms
Abstract This study serves as an investigation of the reliability of symptom data as reported by individuals with chronic fatigue syndrome (CFS), across three recall time frames (the past week, the past month, and the past 6 months), and at … Continue reading
Possible causes of mitochondrial dysfunctions in ME
Abstract Myalgic encephalomyelitis / chronic fatigue syndrome (ME/cfs) is classified by the World Health Organization as a disorder of the central nervous system. ME/cfs is an neuro-immune disorder accompanied by chronic low-grade inflammation, increased levels of oxidative and nitrosative stress … Continue reading
Cytokines and CFS
Abstract A major hypothesis for the cause of chronic fatigue syndrome (CFS) is immune dysregulation, thought to reflect upregulated pro-inflammatory cytokines leading to the symptoms characteristic of this illness. Because symptoms worsen with physical exertion or sleep loss, we hypothesized … Continue reading
Fatigue in cancer and CFS
Abstract BACKGROUND Androgen deprivation therapy (ADT) often worsens fatigue in patients with prostate cancer, producing symptoms similar to chronic fatigue syndrome (CFS). Comparing expression (mRNA) of many fatigue-related genes in patients with ADT-treated prostate cancer versus with CFS versus healthy … Continue reading
Information processing problems in CFS
Research abstract Information processing difficulties are common in patients with chronic fatigue syndrome (CFS). It has been shown that the time it takes to process a complex cognitive task, rather than error rate, may be the critical variable underlying CFS … Continue reading
No evidence that cervical cancer vaccine causes CFS
The Medicines and Healthcare products Regulatory Agency (MHRA) has found no evidence that Cervarix – an HPV vaccine which protects against cervical cancer- causes chronic fatigue syndrome, also known as ME. The MHRA’s scientists conducted their study after reports that … Continue reading
