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Research: Understanding the molecular changes of PEM in ME/CFS
Understanding the molecular changes of Post Exertional Malaise in ME/CFS, by Jemma Elley (Thesis, Bachelor of Biomedical Sciences with Honours). University of Otago, 2021 Research abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating and often life-long condition affecting … Continue reading
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Tagged 2-day exercise test, 8-hydroxy 2 deoxyguanosine, 8-OHdG, Adenosine triphosphate, ATP, DNA methylome, Jemma Elley, machine learning, mitochondrial dysfunction, oxidative stress, oxygen consumption, PEM, Post-exertional malaise, precision medicine, Prof Warren Tate
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A SWATH-MS analysis of ME/CFS peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction
A SWATH-MS analysis of ME/CFS peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction, by Eiren Sweetman, Torsten Kleffmann, Christina Edgar, Michel de Lange, Rosamund Vallings & Warren Tate in Journal of Translational Medicine vol 18, no: 365 (2020) [doi.org/10.1186/s12967-020-02533-3] Research … Continue reading
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Tagged Adenosine triphosphate, ATP profile test, Christina Edgar, Dr Rosamund Vallings, Eiren Sweetman, Michel de Lange, mitochondrial dysfunction, PBMC, peripheral blood mononuclear cells, Prof Warren Tate, Torsten Kleffmann
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Metabolic dysfunction in ME/CFS not due to anti-mitochondrial antibodies
Metabolic dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome not due to anti-mitochondrial antibodies, by Isabell Nilsson, Jeremy Palmer, Eirini Apostolou, Carl-Gerhard Gottfries, Muhammad Rizwan, Charlotte Dahle and Anders Rosén in Front. Med., 31 March 2020 [doi.org/10.3389/fmed.2020.00108 ] Research abstract: Metabolic profiling … Continue reading
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Tagged Adenosine triphosphate, Anders Rosén, autoreactive antibodies, blood lactate accumulation, Carl-Gerhard Gottfries, Charlotte Dahle, Eirini Apostolou, fatigue, Isabell Nilsson, Jeremy Palmer, mitochondrial dysfunction, Muhammad Rizwan, PBC, pDCs, Post-exertional malaise, primary biliary cholngitis, pyruvate dehydrogenase
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Is mitochondrial function abnormal in ME/CFS?
ME Research UK article, 12 January 2017: Is mitochondrial function abnormal? Mitochondria are often referred to as the power plants of the body because they are responsible for generating nearly all the energy needed to support life. These kidney bean-shaped … Continue reading
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Tagged Adenosine triphosphate, ATP, mitochondria, Nick Lawson
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