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Diagnostic test research: Autoantibodies & receptors correlate with symptom severity, autonomic dysfunction & disability in ME/CFS
Autoantibodies to vasoregulative G-Protein-Coupled receptors correlate with symptom severity, autonomic dysfunction and disability in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, by Helma Freitag, Marvin Szklarski, Sebastian Lorenz, Franziska Sotzny, Sandra Bauer, Aurélie Philippe, Claudia Kedor, Patricia Grabowski, Tanja Lange, Gabriela Riemekasten, Harald … Continue reading
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Tagged adrenergic receptors, Aurélie Philippe, autoantibodies, Autoimmunity, Carmen Scheibenbogen, Claudia Kedor, G-protein-coupled receptors, Gabriela Riemekasten, Helma Freitag, Patricia Grabowski, Sandra Bauer, Tanja Lange, vasoregulation
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A unifying hypothesis of the pathophysiology of ME/CFS: recognitions from the finding of autoantibodies against ß2-adrenergic receptors
A unifying hypothesis of the pathophysiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): recognitions from the finding of autoantibodies against ß2-adrenergic receptors, by Klaus Wirth, Carmen Scheibenbogen in Autoimmunity Reviews, online 1 April 2020 [doi.org/10.1016/j.autrev.2020.102527] Research abstract: Myalgic Encephalomyelitis or Chronic … Continue reading
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Tagged abnormal blood circulation, autoantibodies, autoimmune disorders, Carmen Scheibenbogen, Klaus Wirth, M3 acetylcholine receptor, ß2 adrenergic receptor, ß2AdR, vascular dysfunction
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IgG stimulated β2 adrenergic receptor activation is attenuated in patients with ME/CFS
IgG stimulated β2 adrenergic receptor activation is attenuated in patients with ME/CFS, by Jelka Hartwig, Franziska Sotzny, Sandra Bauer, Harald Heidecke, Gabriela Riemekasten, Duska Dragund, Christian Meisel, Claudia Dames, Patricia Grabowski, Carmen Scheibenbogen in Brain, Behavior, & Immunity – Health, 5 … Continue reading
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Tagged autoantibodies, Beta-2 adrenergic receptor, Carmen Scheibenbogen, Christian Meisel, Claudia Dames, Duska Dragund, Franziska Sotzny, Gabriela Riemekasten, Harald Heidecke, IgG antibodies, immunoglobulin, Jelka Hartwig, Patricia Grabowski, Sandra Bauer, β2 adrenergic receptor
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Antibodies to adrenergic & muscarinic receptors in ME/CFS
Blog post, by Paolo Maccallini, 29 August 2017: Antibodies to adrenergic and muscarinic receptors in ME/CFS, During the Community Symposium on the molecular basis of ME/CFS two different groups of researchers reported on the increased level of antibodies to beta adrenergic and … Continue reading
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Tagged adrenergic receptors, autoantibodies, Autoimmunity, molecular mimicry, muscarinic receptors, Paolo Maccallini, Prof Alan Light, Prof Jonas Bergquist
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A proposal for treatment of harmful auto-antibodies in auto-immune disorders
Research abstract: The hypothesis proposed is that functional disorders, such as irritable bowel syndrome, chronic fatigue syndrome and anorexia nervosa are caused by auto-antibodies to neuronal proteins induced by molecular mimicry with microbial antigens. The age incidence of these conditions, … Continue reading
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Tagged autoantibodies, autoimmune disorders, bacteria, flies, JA Morris, molecular mimicry, Q Wessels, SJ Broughton
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Anti-citrullinated protein antibodies in CFS
The Vermont CFIDS Association reports on a recent pilot study and invites contributions to enable further research: While preliminary, the results from this University of Vermont study is the first evidence for the potential existence of autoantibodies in ME/CFS, indicative … Continue reading
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Tagged anti-citrullinated protein antibodies, autoantibodies, David Maughan, George Webb, immune system dysfunction, inflammation, Mercedes Rincon, Terence Naumann, Vermont CFIDS Association
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Elevated autoantibodies found in CFS subgroup
Research highlights: β adrenergic and muscarinic acetylcholine receptor autoantibodies are elevated in a subset of patients with Chronic Fatigue Syndrome (CFS). Elevated autoantibodies in CFS correlate with elevated IgG1-3 subclass levels, thyreoperoxidase and ANA antibodies and T cell activation. In … Continue reading
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Tagged autoantibodies, autoimmune disorders, Dr Oystein Fluge, Prof Olav Mella, Receptors, rituximab, subgroup, T-cell
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