Tag Archives: Dr Sonya Marshall-Gradisnik

Research review: Biomarkers for ME/CFS

Biomarkers for ME/CFS: a systematic review   Australian researchers found 101 key studies in ME/CFS that varied in efficacy, quality, and potential to be developed into a diagnostic biomarker. Most were blood-based and measured a range of dysfunction. “Many of … Continue reading

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Research: fMRI reveals differences between ME/CFS diagnostic criteria

fMRI distinguishes between two classes of ME/CFS   Australian researchers have discovered that patients diagnosed using 2 different criteria, International Consensus Criteria (ICC) and the Fukuda criteria, have different brain activity. The main difference between the 2 criteria is that … Continue reading

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Understanding ME (and Long COVID)

Understanding Myalgic Encephalomyelitis – Myalgic Encephalomyelitis and Long COVID have overlapping presentation   Dr Sonya Marshall-Gradisnik and Dr Natalie Eaton-Fitch from Griffith University, on the Gold Coast in Australia, say there is a significant overlap in symptoms and possibly the … Continue reading

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Research: Impaired TRPM3 ion channel function found in ME/CFS & Long COVID

TRPM3 dysfunction in post COVID-19 condition and ME/CFS patients   Research from the NCNED in Australia, using their Electrophysiology ‘Patch Clamp’ technique, concludes: The results of this investigation suggest that post COVID-19 condition patients may have impaired TRPM3 ion channel … Continue reading

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Cognitive dysfunction research: Hippocampal subfields & ME/CFS

Volumetric differences in hippocampal subfields and associations with clinical measures in myalgic encephalomyelitis/chronic fatigue syndrome, by Kiran Thapaliya, Donald Staines, Sonya Marshall- Gradisnik, Jiasheng Su, Leighton Barnden in Journal of Neuroscience Research March 31, 2022     “The hippocampus is … Continue reading

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Treatment research: …restoration using Naltrexone in natural killer cells of ME/CFS patients

Impaired TRPM3-dependent calcium influx and restoration using Naltrexone in natural killer cells of myalgic encephalomyelitis/chronic fatigue syndrome patients, by Natalie Eaton-Fitch, Stanley Du Preez, Hélène Cabanas, Katsuhiko Muraki, Donald Staines & Sonya Marshall-Gradisnik in Journal of Translational Medicine volume 20, … Continue reading

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Research: Analysis of post COVID-19 & its overlap with ME/CFS

Long COVID overlap with ME/CFS   A group of researchers from around the world have joined together to analyse long COVID’s symptom overlap with ME/CFS. Highlights Serious side effects and post-infection sequelae have been reported in SARS-CoV-2-infected patients after acute … Continue reading

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Research: The characterization of IL-2 stimulation & treatment of TRPM3… in ME/CFS

Characterization of IL-2 stimulation and TRPM7 pharmacomodulation in NK Cell cytotoxicity and channel Co-Localization with PIP2 in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome patients, by Stanley Du Preez , Natalie Eaton-Fitch, Helene Cabanas, Donald Staines and Sonya Marshall-Gradisnik in Int. J. … Continue reading

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Research: Impact of life stressors on ME/CFS symptoms

Impact of life stressors on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome symptoms: An Australian longitudinal study, by  Cassandra Balinas, Natalie Eaton-Fitch, Rebekah Maksoud, Donald Staines, and Sonya Marshall-Gradisnik in Int. J. Environ. Res. Public Health 2021, 18(20) [10.3390/ijerph182010614] (This article belongs to the … Continue reading

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Research: Diffusion tensor imaging (MRI) reveals neuronal microstructural changes in ME/CFS

Diffusion tensor imaging reveals neuronal microstructural changes in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, by Kiran Thapaliya, Sonya Marshall-Gradisnik, Don Staines, Leighton Barnden in European Journal of Neuroscience, August 6, 2021 [doi/10.1111/ejn.15413]   Research abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients suffer from … Continue reading

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