Tag Archives: PACE trial
The problem of bias in behavioural intervention studies: lessons from the PACE trial
Abstract: The problem of bias in behavioural intervention studies: Lessons from the PACE trial, by Carolyn Wilshire in Journal of Health Psychology [Preprint 23 March 2017] Geraghty’s recent editorial on the PACE trial for chronic fatigue syndrome has stimulated a lively … Continue reading
How a study about CFS was doctored, adding to pain and stigma
The Conversation blog, by Steven Lubet, 23 March 2017: How a study about Chronic Fatigue Syndrome was doctored, adding to pain and stigma The public relies on scientists to report their findings accurately and completely, but that does not always happen. … Continue reading
Do graded activity therapies cause harm in CFS?
Article abstract: Reporting of harms was much better in the PACE (Pacing, graded Activity, and Cognitive behavioural therapy: a randomised Evaluation) trial than earlier chronic fatigue syndrome trials of graded exercise therapy and cognitive behavioural therapy. However, some issues remain. The … Continue reading
PACE trial claims of recovery are not justified by the data: a rejoinder to Sharpe, Chalder, Johnson, Goldsmith & White
Following a response from the PACE trial researchers to their re-analysis from the PACE trial researchers Wilshire et al have published a reply: Article abstract: BACKGROUND: Recently, we critically evaluated the claim from the PACE trial that cognitive behavioural therapy (CBT) and graded … Continue reading
The full independent re-analysis of the PACE Trial now available on open access
ME Association blog post, 22 March 2017: Thanks to the MEA, you can now read the whole independent re-analysis of the PACE Trial recovery paper, 22 March 2017 The independent re-analysis of the PACE Trial recovery paper emerged from behind the … Continue reading
New York Times: Getting it wrong on CFS
New York Times article, by Julie Rehmeyer and David Tuller, 18 March 2017: Getting It wrong on Chronic Fatigue Syndrome What are some of the treatment regimens that sufferers of chronic fatigue syndrome should follow? Many major medical organizations cite … Continue reading
Children with ME need relevant science, not pressure to do more, more, more
Bristol cable article, by Jenny Horner, 24 January 2017: Children with ME need relevant science, not pressure to do more, more, more” An advocate and campaigner living with ME explains why she opposes Bristol University’s trials on children with the … Continue reading
PACE trial data assessment: in ME/CFS CBT and GET are ineffective
Research abstract: The PACE trial concluded that Cognitive Behavioral Therapy (CBT) and Graded Exercise Therapy (GET) are moderately effective in managing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and yielded a 22% recovery rate. Nonetheless, the recently released individual participant data shows … Continue reading
Can patients with CFS really recover after GET or CBT?
Research abstract: BACKGROUND: Publications from the PACE trial reported that 22% of chronic fatigue syndrome patients recovered following graded exercise therapy (GET), and 22% following a specialised form of CBT. Only 7% recovered in a control, no-therapy group. These figures … Continue reading
Dr Phil Hammond writes about the ME campaigners’ challenge to the science of CBT & GET
Private eye Medicine Balls column, 10 December 2016: ‘ME campaigners don’t ignore CBT and GET… but they do challenge the science’ Private eye Medicine Balls column, 25 November 2016: ‘ME cluster bomb’ [Written by ‘M.D.’, the nom de plume of Dr Phil … Continue reading
