Tag Archives: PACE trial

David Tuller writes to the CFS/ME Research Collaborative re libel charge

Virology blog post , Dr David Tuller, 8 May 2017: Trial By Error, Continued: An Open Letter to the Board of the CFS/ME Research Collaborative To Members of the Board of the CMRC: Not long ago, at the annual conference … Continue reading

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PLOSone journal ‘expression of concern’ about PACE authors’ unwillingness to share data

Expression of Concern: Adaptive Pacing, Cognitive Behaviour Therapy, Graded Exercise, and Specialist Medical Care for Chronic Fatigue Syndrome: A Cost-Effectiveness Analysis, by the PLOS ONE Editors in PLoS ONE 12(5)e0177037 [Published: May 2, 2017] Several readers have raised concerns about … Continue reading

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Dr Shepherd says ‘It’s time for an independent review of the PACE Trial methods & results’

Article abstract: PACE trial claims for recovery in myalgic encephalomyelitis/chronic fatigue syndrome – true or false? It’s time for an independent review of the PACE Trial methods and results, by Charles Bernard Shepherd in Journal of Health Psychology, 10 April 2017 The … Continue reading

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PACE team response shows a disregard for the principles of science

Prof Jonathan Edwards (UK) and Prof David Tuller (USA) add to the growing number of articles by clinicians and researchers challenging the scientific credentials of the PACE researchers. PACE team response shows a disregard for the principles of science, by Prof Jonathan Edwards … Continue reading

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The problem of bias in behavioural intervention studies: lessons from the PACE trial

Abstract: The problem of bias in behavioural intervention studies: Lessons from the PACE trial, by Carolyn Wilshire in Journal of Health Psychology [Preprint 23 March 2017] Geraghty’s recent editorial on the PACE trial for chronic fatigue syndrome has stimulated a lively … Continue reading

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How a study about CFS was doctored, adding to pain and stigma

The Conversation blog, by Steven Lubet, 23 March 2017: How a study about Chronic Fatigue Syndrome was doctored, adding to pain and stigma  The public relies on scientists to report their findings accurately and completely, but that does not always happen. … Continue reading

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An open letter re PACE trial to Psychological Medicine, again!

Virology blog post, by Prof Vincent Racaniello, 23 March 2017: An open letter to Psychological Medicine, again! Last week, Virology Blog posted an open letter to the editors of Psychological Medicine. The letter called on them to retract the misleading … Continue reading

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Do graded activity therapies cause harm in CFS?

Article abstract: Reporting of harms was much better in the PACE (Pacing, graded Activity, and Cognitive behavioural therapy: a randomised Evaluation) trial than earlier chronic fatigue syndrome trials of graded exercise therapy and cognitive behavioural therapy. However, some issues remain. The … Continue reading

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PACE trial claims of recovery are not justified by the data: a rejoinder to Sharpe, Chalder, Johnson, Goldsmith & White

Following a response from the PACE trial researchers to their re-analysis from the PACE trial researchers Wilshire et al have published a reply: Article abstract:  BACKGROUND: Recently, we critically evaluated the claim from the PACE trial that cognitive behavioural therapy (CBT) and graded … Continue reading

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The full independent re-analysis of the PACE Trial now available on open access

ME Association blog post, 22 March 2017: Thanks to the MEA, you can now read the whole independent re-analysis of the PACE Trial recovery paper, 22 March 2017 The independent re-analysis of the PACE Trial recovery paper emerged from behind the … Continue reading

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