Tag Archives: phenotypes

CFS/ME symptom-based phenotypes & 1 year treatment outcomes in UK & Netherlands

Research abstract: Chronic fatigue syndrome (CFS/ME) symptom-based phenotypes and 1-year treatment outcomes in two clinical cohorts of adult patients in the UK and The Netherlands, by  Simon M. Collin, Jon Heron, Stephanie Nikolaus, Hans Knoop, Esther Crawley in Journal of Psychosomatic Research Vol. 104, … Continue reading

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Are current CFS criteria diagnosing different disease phenotypes?

Research abstract: Are current chronic fatigue syndrome criteria diagnosing different disease phenotypes? by Laura Maclachlan, Stuart Watson, Peter Gallagher, Andreas Finkelmeyer, Leonard A. Jason, Madison Sunnquist, Julia L. Newton, in PLoS ONE 12(10) [Published: October 20, 2017] Importance: Chronic fatigue syndrome … Continue reading

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CFS symptom profiles in UK & Netherlands

Research highlights: • We explore chronic fatigue syndrome (CFS) phenotypes in two large clinical cohorts. • Adults with CFS may have one of 6 symptom-based phenotypes. • Phenotypes were associated with sex, duration of illness, and comorbidity. • Polysymptomatic patients … Continue reading

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Characterisation of impaired NK cells in CFS/ME

Abstract OBJECTIVE Natural Killer (NK) cells are classified into different phenotypes according to the expression of the surface markers CD56 and CD16. Each NK cell phenotype has a role in the immune response through cytotoxic activity or cytokine production. Reduced … Continue reading

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Review of biomarkers in CFS

Abstract Chronic fatigue syndrome (CFS) remains an incompletely characterized illness, in part due to controversy regarding its definition, biological basis, and diagnosis. Biomarkers are objective measures that may lead to improvements in our understanding of CFS by providing a more … Continue reading

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