Tag Archives: cortisol

Characterization of cortisol dysregulation in FM & CFS: a state-space approach

Characterization of Cortisol Dysregulation in Fibromyalgia and Chronic Fatigue Syndromes: A State-Space Approach, by Divesh Deepak Pednekar, Md. Rafiul Amin, Hamid Fekri Azgomi, Kirstin Aschbacher, Leslie J Crofford, Rose T Faghih in Published in: IEEE Transactions on Biomedical Engineering PP(99):1-1 · … Continue reading

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Reduction of glucocorticoid receptor function in CFS – no causal link to childhood trauma

Research abstract: Reduction of glucocorticoid receptor function in CFS, by Megan Lynn, Laura Maclachlan, Andreas Finkelmeyer, James Clark, James Locke, Stephen Todryk, Wan-Fai Ng, Julia L Newton, Stuart Watson in Mediators of Inflammation [Preprint April 20, 2018] Glucocorticoid receptor (GR) function may … Continue reading

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NEID disease? Study suggests neuro, endocrine & immune systems work together to produce ME/CFS

Simmaron Research blog post, by Cort Johnson, 26 January 2018: NEID Disease? Study Suggests Neuro, Endocrine and Immune Systems Work Together to Produce ME/CFS   Bruun Wyller continues to surprise. When last heard from this erstwhile cognitive behavioral therapy (CBT) … Continue reading

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Neuroendocrine disorder in CFS

Research abstract: Neuroendocrine disorder in chronic fatigue syndrome, by Slavica TOMIC, Snezana BRKIC, Dajana LENDAK, Daniela MARIC, Milica MEDIC STOJANOSKA, Aleksandra NOVAKOV MIKIC in Turkish Journal of Medical Sciences (2017) 47: sag-1601-110  [Published Online: 17 Dec 2016] Background/aim: Neuroendocrine disorders are … Continue reading

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FM and CFS: underlying biology

Article abstract: There is an increasing interest in understanding the biological mechanism underpinning fibromyalgia (FM) and chronic fatigue syndrome (CFS). Despite the presence of mixed findings in this area, a few biological systems have been consistently involved, and the increasing number … Continue reading

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Relationship between insomnia and CFS/ME

Research abstract Fatigue is common in the general population, and is the hallmark of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). Although the occurrence of sleep difficulties is known to be common in subjects with fatigue, research on insomnia in such subjects … Continue reading

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Hypocortisolism in CFS adolescents responds to treatment

Abstract BACKGROUND: There is accumulating evidence of hypothalamic-pituitary-adrenal (HPA) axis hypofunction in chronic fatigue syndrome (CFS). However, knowledge of this hypofunction has so far come exclusively from research in adulthood, and its clinical significance remains unclear. The objective of the … Continue reading

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