Author Archives: wames
Support for the microgenderome invites enquiry into sex differences in ME/CFS
Research abstract: The microgenderome defines the interaction between microbiota, sex hormones and the immune system. Our recent research inferred support for the microgenderome by showing sex differences in microbiota-symptom associations in a clinical sample of patients with myalgic encephalomyelitis / … Continue reading
Robust evidence of an underlying biological process in ME/CFS
Miriam Tucker reports on the overwhelming evidence for the biological basis for ME/CFS which was presented at the IACFS/ME conference in the USA in October 2016: Biomarker Research Advances in ‘Chronic Fatigue Syndrome’, by Miriam E. Tucker in Medscape Medical … Continue reading
Investigation of the effects of vanilloids in animal model of chronic fatigue
Research abstract: AIM OF THE STUDY: To assess the effectiveness of TRPV1 modulators in animal model of Chronic fatigue syndrome (CFS). To assess central and peripheral behavioral activity of TRPV1 modulators. MATERIAL AND METHODS: CFS was induced by forcing the rats to … Continue reading
New Australian genetic marker detection study
ME Research UK blog post, 6 November 2016: New study – Genetic marker detection Prof Brett Lidbury and colleagues at the John Curtin School of Medical Research, Australian National University in Canberra are conducting an ongoing programme, funded by charities in … Continue reading
Hypothalamic-Pituitary-Adrenal Hypofunction in ME/CFS
Review abstract: There is evidence that immune-inflammatory and oxidative and nitrosative stress (O&NS) pathways play a role in the pathophysiology of myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS). There is also evidence that these neuroimmune diseases are accompanied by hypothalamic-pituitary-adrenal (HPA) axis … Continue reading
Studies on CBT & GET for ME/CFS are misleading, says Swedish prof
Article abstract: There have been a number of studies on Cognitive Behavioral Therapy (CBT) and Graded Exercise Therapy (GET) for ME/CFS based on a treatment model where the disease is perpetuated by cognitive processes. Although the studies are flawed and … Continue reading
Dr Keith Geraghty requests experiences of CBT & GET
Dr Keith Geraghty, researcher at the University of Manchester (@keithgeraghty) has tweeted at 6:09 p.m. on Mon, Nov 07, 2016: Ever experience adverse reactions to CBT or GET in CFS treatment – email me @ Keith.geraghty@manchester.ac.uk – we want to hear … Continue reading
Postexertion ‘crash,’ not fatigue per se, marks CFS
Medscape Medical News article, by Miriam Tucker, November 04, 2016: Post exertion ‘Crash,’ not Fatigue per se, Marks Syndrome Article extract: The name “chronic fatigue syndrome” is being phased out not just because it is viewed as trivializing a condition that renders … Continue reading
PACE-gate: when clinical trial evidence meets open data access
Article abstract: Science is not always plain sailing and sometimes the voyage is across an angry sea. A recent clinical trial of treatments for chronic fatigue syndrome (the PACE trial) has whipped up a storm of controversy. Patients claim the … Continue reading
