Category Archives: News

Quantum leap in viral detection could impact ME/CFS & FM

Breakthrough findings in an individual disorder are special, but developing new technology that expands our ability to understand many diseases is something else entirely. It provides the potential to make a difference on a truly vast scale. Those types of … Continue reading

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Natural killer cytotoxicity in CFS

 Research abstract: Natural killer (NK) cytotoxicity of chronic fatigue syndrome (CFS) patients is decreased, as reported by several laboratories. This observation led us to query whether the NK cells also lack antibody-dependent cell-mediated cytotoxicity (ADCC). NK cells have the IgG … Continue reading

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The relationship between IBS, dyspepsia, chronic fatigue and overactive bladder syndrome

Research article abstract: Background: To investigate in a cohort with previous gastrointestinal infection and a control group the prevalence of overactive bladder syndrome (OAB), and how it was associated with three other functional disorders; irritable bowel syndrome (IBS), functional dyspepsia … Continue reading

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Fatigue is prevalent and debilitating in patients with mitochondrial disease

Highlights Perceived fatigue is a prominent and often debilitating symptom in patients with mitochondrial disease. Perceived fatigue correlates with disease severity but not genotype. Excessive sleepiness is prevalent but dissociated with perceived fatigue in patients with mitochondrial disease. Perceived fatigue … Continue reading

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Dysfunctional energy metabolism and oxidative stress pathways in CFS

Research abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating long-term multisystem disorder with a central and inexplicably persistent fatigue symptom that is unable to be relieved by rest. Energy metabolism and oxidative stress have been recent focal points of … Continue reading

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The effect of submaximal exercise tests in ME/CFS

Research abstract: BACKGROUND Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating illness. Symptoms include profound fatigue and distinctive post-exertional malaise (PEM). We asked whether a submaximal exercise test would prove useful for identifying different patterns of tissue oxygen utilization in … Continue reading

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Dysfunction found in innate and adaptive immune systems in CFS/ME

Research abstract: Background: Abnormal immune function is often an underlying component of illness pathophysiology and symptom presentation. Functional and phenotypic immune-related alterations may play a role in the obscure pathomechanism of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). The objective of this … Continue reading

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Computerised training improves verbal working memory in ME/CFS

Research abstract: OBJECTIVE: Patients with myalgic encephalomyelitis/chronic fatigue syndrome experience cognitive difficulties. The aim of this study was to evaluate the effect of computerized training on working memory in this syndrome. DESIGN: Non-randomized (quasi-experimental) study with no-treatment control group and … Continue reading

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Case study of yoga and CFS

Case study abstract: BACKGROUND AND OBJECTIVE: Chronic Fatigue Syndrome (CFS) is characterized by excessive fatigue after minimal physical or mental exertion, muscle and joint pain, poor concentration, dizziness, and sleep disturbances. We report here the effect of a yoga-based lifestyle intervention … Continue reading

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Variability in symptoms complicates usefulness of case definitions

Research abstract: Background: Ambiguities in case definitions have created difficulties in replicating findings and estimating the prevalence rates for chronic fatigue syndrome (CFS) and Myalgic Encephalomyelitis (ME). Purpose: The current study examined differences in occurrence rates for CFS and ME … Continue reading

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