Category Archives: News

Review of exercise therapy studies

Review abstract BACKGROUND: Chronic fatigue syndrome (CFS) is characterised by persistent, medically unexplained fatigue, as well as symptoms such as musculoskeletal pain, sleep disturbance, headaches and impaired concentration and short-term memory. CFS presents as a common, debilitating and serious health … Continue reading

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Immune biomarkers discussion

A team of American scientists discuss Prof Mady Hornig’s recent research on immune signatures in ME/CFS. They review identification of immune biomarkers in CFS/ME patients, and how a cell nuclease controls the innate immune response to vaccinia virus infection. [Introductions last about … Continue reading

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Appropriate management of FM & CFS can give moderate improvements

Research abstract: Fibromyalgia and chronic fatigue syndrome represent two of the most commonly encountered functional somatic syndromes in clinical practice. Both have been contentious diagnoses in the past, and this diagnostic dispute has resulted in a therapeutic nihilism that has … Continue reading

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Sleep/wake behaviour in ME/CFS

Research abstract: Sleep dysfunction is a prominent feature in the subjective experience of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Although studies using polysomonography have identified at least one abnormal sleep characteristic in individuals with ME/CFS, no standard abnormalities in sleep have … Continue reading

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Why exercise magnifies exhaustion in CFS

Study shows why exercise magnifies exhaustion for chronic fatigue syndrome patients [March 12 2015] The mechanism that causes high-performance athletes to “feel the burn” turns out to be the culprit in what makes people with chronic fatigue syndrome feel exhausted by … Continue reading

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The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders

Article abstract Background: Mitochondrial dysfunction and defects in oxidative metabolism are a characteristic feature of many chronic illnesses not currently classified as mitochondrial diseases. Examples of such illnesses include bipolar disorder, multiple sclerosis, Parkinson’s disease, schizophrenia, depression, autism, and chronic … Continue reading

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Medicinal cannabis and ME

Sittingbourne-based Netflix documentary producer Jason Reed speaks out: online article at  Kent online, 24 March 2015 Jason Reed, who suffers from M.E. has spoken extensively on the uses of medicinal cannabis. “To feel the literal definition of exhaustion, to have … Continue reading

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Post-exertional muscle abnormalities in CFS

Research abstract Background: Post exertional muscle fatigue is a key feature in Chronic Fatigue Syndrome (CFS). Abnormalities of skeletal muscle function have been identified in some but not all patients with CFS. To try to limit potential confounders that might … Continue reading

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Cognitive dysfunction in adolescents with chronic fatigue

Research abstract: OBJECTIVE: To compare cognitive function in adolescents with chronic fatigue with cognitive function in healthy controls (HC). STUDY DESIGN: Cross-sectional study. SETTING: Paediatric department at Oslo University Hospital, Norway. PARTICIPANTS: 120 adolescents with chronic fatigue (average age 15.4 … Continue reading

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CFS subgroup found to have low level inflammation

CFS is characterized by profound levels of persistent/recurrent fatigue. It is proposed that chronic, low level inflammation may play a role in this fatigue. We recruited 100 untreated patients with CFS (average age 33±12) and 100 age and sex matched … Continue reading

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