Category Archives: News

Role of polymorphisms of inducible nitric oxide synthases in idiopathic environmental intolerances

Research abstract: Oxidative stress and inflammation play a pathogenetic role in idiopathic environmental intolerances (IEI), namely, multiple chemical sensitivity (MCS), fibromyalgia (FM), and chronic fatigue syndrome (CFS). Given the reported association of nitric oxide synthase (NOS) gene polymorphisms with inflammatory … Continue reading

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HPV vaccine is suspected cause of POTs

Research abstract: BACKGROUND Infections with human papilloma virus (HPV) can result in cervical, oropharyngeal, anal, and penile cancer and vaccination programs have been launched in many countries as a preventive measure. We report the characteristics of a number of patients … Continue reading

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Response to Vitamin B12 and folic acid in ME and FM

Research abstract: BACKGROUND: Patients with myalgic encephalomyelitis (ME, also called chronic fatigue syndrome) may respond most favorably to frequent vitamin B12 injections, in vital combination with oral folic acid. However, there is no established algorithm for individualized optimal dosages, and … Continue reading

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Effect of household tasks on people with chronic fatigue & their partners

Research abstract: This study examined salivary cortisol levels in couples in which one member had unexplained chronic fatigue (CF). The couples completed questionnaires and seven household activities in a laboratory setting and provided salivary cortisol samples prior to and immediately … Continue reading

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CBT & GET in clinical practice

Research abstract: BACKGROUND Studies have reported that Cognitive Behavioural Therapy (CBT) and Graded Exercise Therapy (GET) are effective treatments for Chronic Fatigue Syndrome (CFS). METHOD One hundred and seventy-one patients undertook a course of either CBT (n = 116) or … Continue reading

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Pregabalin useful for chronic pain

Research abstract Pregabalin is frequently prescribed for chronic non-cancer pain. No previous study has examined its off-label use. Objectives: Our primary aim was to assess the proportion of patients taking pregabalin for conditions approved by Health Canada (“on-label”) and compare … Continue reading

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CFS & FM in sleep disorders

Research abstract: Background: Since chronic fatigue syndrome (CFS) and fibromyalgia (FM) often co-exist, some believe they reflect the same process, somatization. Against that hypothesis are data suggesting FM but not CFS was common in patients with sleep-disordered breathing (SDB). The … Continue reading

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FM and CFS: underlying biology

Article abstract: There is an increasing interest in understanding the biological mechanism underpinning fibromyalgia (FM) and chronic fatigue syndrome (CFS). Despite the presence of mixed findings in this area, a few biological systems have been consistently involved, and the increasing number … Continue reading

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Muscle cell abnormalities in CFS: AMPK & IL6

Research abstract: Background: Post exertional muscle fatigue is a key feature in Chronic Fatigue Syndrome (CFS). Abnormalities of skeletal muscle function have been identified in some but not all patients with CFS. To try to limit potential confounders that might … Continue reading

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Mindfulness as effective as anti-depressants for depression

From the BBC website: A mindfulness-based therapy could offer a “new choice for millions of people” with recurrent depression, a Lancet report suggests. Scientists tested it against anti-depressant pills for people at risk of relapse and found it worked just … Continue reading

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