Category Archives: News

Fatigue in OI subgroup improves with modafinil

Abstract Many patients who suffer from orthostatic intolerance (OI) may also have severe fatigue and extreme exercise intolerance. In some of these patients, fatigue may be so severe that they are unable to maintain employment. In some, even the activities … Continue reading

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MRI finds heart dysfunction in CFS

Abstract Purpose: In chronic fatigue syndrome (CFS), only a few imaging and histopathological studies previously assessed either cardiac dimensions/function or myocardial tissue, suggesting smaller left ventricular (LV) dimensions, LV wall motion abnormalities (WMA), and occasionally viral persistence that may lead … Continue reading

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Warning against overstating recovery in CFS PACE trial

Commenting on a recently published report of a large-scale evaluation of behavioral interventions for chronic fatigue syndrome (CFS), Fred Friedberg, PhD and Jenna Adamowicz warned against overstating the capacity of any currently available therapy to produce recovery from CFS. In … Continue reading

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Irritable bowel syndrome and chronic fatigue 6 years after Giardia infection

ABSTRACT Background: Functional gastrointestinal disorders and fatigue may follow acute infections. This study aimed to estimate the persistence, prevalence and risk of irritable bowel syndrome and chronic fatigue six years after Giardia infection. Methods: Controlled prospective study of a cohort … Continue reading

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ME Cover up – Severe ME Day August 8th 2014

the ME cover up Many people with ME feel they are invisible to the outside world and that ME is not taken seriously. “We may not be able to present ourselves to the world because of severe ill health but … Continue reading

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Chronic fatigue and RLS can be caused by iron deficiency

Iron deficiency (absolute or functional) is commonly observed (frequently without associated anemia) in up to one third of old people. Iron deficiency is the most cause of anemia in adults. Many non hematological consequences of iron deficiency are described like: … Continue reading

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Lyme disease becoming more widespread & needs new healthcare approach

Abstract Lyme disease, caused by Borrelia burgdorferi and transmitted by ticks, was initially considered a recent, rare and regional occurrence. We now have evidence that very similar bacteria infected humans in Europe during the ice age (Keller et al., 2012). … Continue reading

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Joint hypermobility and autonomic hyperactivity common in CFS, IBS, FM etc.

Abstract Objective To test the hypothesis that Joint hypermobility and autonomic dysfunction are over-expressed within neurodevelopmental disorders. Joint hypermobility is a widespread poorly recognized connective tissue condition with affected individuals overrepresented among panic and anxiety disorders, irritable bowel syndrome, fibromyalgia, … Continue reading

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Human herpesvirus 6 and the nervous system

Human herpesvirus (HHV)-6 is a β-herpesvirus that infects most infants by 2 years of age and persists in a variety of host cells after primary infection, with intermittent reactivation typically during periods of immunosuppression. HHV-6 has two closely related species, … Continue reading

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DSQ is valid tool for assessing symptoms in ME/CFS

Abstract Background: The diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is complex and largely based on self-reported symptom profiles. The field lacks consensus for a singular case definition and heterogeneous samples make comparability across studies difficult. Purpose: The present study … Continue reading

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