Category Archives: News
Mitochondrial dysfunction and fatigue review
Abstract Fatigue is often described by patients as a lack of energy, mental or physical tiredness, diminished endurance, and prolonged recovery after physical activity. Etiologic mechanisms underlying fatigue are not well understood; however, fatigue is a hallmark symptom of mitochondrial … Continue reading
Review of the role of T cells in the ME/CFS immune system
Abstract Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a multifactorial disorder defined by symptom-specific criteria and characterised by severe and prolonged fatigue. CFS/ME typically affects a variety of bodily systems, including the immune system. Patients with CFS/ME exhibit significantly reduced Natural … Continue reading
Cardiac dysfunction with a small heart is related to ME
Abstract The etiology of chronic fatigue syndrome (CFS) is unknown. Myalgic encephalomyelitis (ME) has been recently postulated to be the cause of CFS. Orthostatic intolerance (OI) has been known as an important symptom in predicting quality of life in CFS … Continue reading
Symptoms of Meares-Irlen/Visual Stress Syndrome in CFS
Abstract Several diagnostic symptoms of the visual-processing deficit Meares-Irlen/Visual Stress Syndrome are remarkably similar to symptom manifestations reported by individuals with chronic fatigue syndrome (CFS). We surveyed the specific incidences of nine widely-recognised symptoms of visual stress (VS) in a … Continue reading
Home-based self-management program suitable for chronic fatigue
Abstract Purpose: This study evaluated the feasibility of a 12-week home-based self-management program for unexplained chronic fatigue (UCF) or chronic fatigue syndrome (CFS). Methods: Self-report outcomes included measures of fatigue impact, physical function, depression, and global change. A web diary … Continue reading
Repeated exercise tests have role as diagnostic test for ME/CFS
Abstract (provisional) Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a multi-system illness characterized, in part, by increased fatigue following minimal exertion, cognitive impairment, poor recovery to physical and other stressors, in addition to other symptoms. Unlike healthy subjects and other … Continue reading
Better ways of assessing severity of illness and treatment outcomes needed for children with CFS/ME
Abstract Chronic Fatigue Syndrome or Myalgic Encephalomyelitis (CFS/ME) in children is characterized by persistent or recurrent debilitating fatigue which results in a substantial reduction in activity. There is a growing interest in the use of questionnaires, or patient-reported outcome measures … Continue reading
Increased risk of CFS following shingles
Abstract Chronic fatigue syndrome (CFS) is a complex disorder accompanied by unexplainable persistent fatigue, in which several etiological factors exist, such as viral infections. Using the National Health Insurance Research Database (NHIRD) of Taiwan, this study evaluated the association between … Continue reading
Brain scans detect neuroinflammation in CFS
Abstract Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a disease characterized by chronic, profound, disabling, and unexplained fatigue. Although it is hypothesized that brain inflammation is involved in the pathophysiology of CFS/ME, there is no direct evidence of neuroinflammation in patients … Continue reading
The role of illness acceptance and neuroticism in CFS on quality of life
Abstract OBJECTIVE Increasing the quality of life (QoL) of patients with chronic fatigue is challenging because recovery is seldom achieved. Therefore, it is important to identify processes that improve QoL. This study examined the extent of improvement related to cognitive … Continue reading
