Category Archives: News
Scientific American highlights brain inflammation studies
Researchers might soon redefine the mysterious condition, while the latest findings point to the role of brain inflammation by Katherine Harmon Courage in Scientific American, May 16, 2014 More than one million people in the U.S. suffer from a poorly … Continue reading
Defining recovery in CFS: a review
Abstract Purpose In chronic fatigue syndrome (CFS), the lack of consensus on how recovery should be defined or interpreted has generated controversy and confusion. The purpose of this paper was to systematically review, compare, and evaluate the definitions of recovery … Continue reading
Gwyn’s 7 day sponsored walk
Recovered ME sufferer Gwyneth Hopkins will walk round Pembrokeshire for 7 days from May 11th – 17th. She plans to start at Haverfordwest at 10am Sunday 11th May, then go around the top of Cleddau estuary to Lawrenny ,then Lydstep, … Continue reading
Hypocortisolism in CFS adolescents responds to treatment
Abstract BACKGROUND: There is accumulating evidence of hypothalamic-pituitary-adrenal (HPA) axis hypofunction in chronic fatigue syndrome (CFS). However, knowledge of this hypofunction has so far come exclusively from research in adulthood, and its clinical significance remains unclear. The objective of the … Continue reading
Review of biomarkers in CFS
Abstract Chronic fatigue syndrome (CFS) remains an incompletely characterized illness, in part due to controversy regarding its definition, biological basis, and diagnosis. Biomarkers are objective measures that may lead to improvements in our understanding of CFS by providing a more … Continue reading
Post-exertional symptom exacerbation follows mental effort in ME/CFS
Abstract Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating, long-term condition characterised by extreme fatigue (worsened by exertion), muscle and joint pain, and sleep disturbance. Post-exertional fatigue has been demonstrated previously following physical exercise, but not from mental exertion … Continue reading
Mitochondrial dysfunction and fatigue review
Abstract Fatigue is often described by patients as a lack of energy, mental or physical tiredness, diminished endurance, and prolonged recovery after physical activity. Etiologic mechanisms underlying fatigue are not well understood; however, fatigue is a hallmark symptom of mitochondrial … Continue reading
Review of the role of T cells in the ME/CFS immune system
Abstract Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a multifactorial disorder defined by symptom-specific criteria and characterised by severe and prolonged fatigue. CFS/ME typically affects a variety of bodily systems, including the immune system. Patients with CFS/ME exhibit significantly reduced Natural … Continue reading
Cardiac dysfunction with a small heart is related to ME
Abstract The etiology of chronic fatigue syndrome (CFS) is unknown. Myalgic encephalomyelitis (ME) has been recently postulated to be the cause of CFS. Orthostatic intolerance (OI) has been known as an important symptom in predicting quality of life in CFS … Continue reading
