Category Archives: News

Shared microglial mechanisms underpinning depression & CFS & their comorbidities

Shared microglial mechanisms underpinning depression and chronic fatigue syndrome and their comorbidities, by Adriano José Maia Chaves-Filho, Danielle S Macedo, David Freitas de Lucena, Michael Maes in Behavioural Brain Research Vol 372, 17 October 2019, 111975 [https://doi.org/10.1016/j.bbr.2019.111975]   Research abstract: … Continue reading

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Neuroimmunology: what role for autoimmunity, neuroinflammation, & small fiber neuropathy in FM, CFS, & adverse events after HPV?

Neuroimmunology: what role for autoimmunity, neuroinflammation, and small fiber neuropathy in Fibromyalgia, Chronic Fatigue Syndrome, and adverse events after Human Papillomavirus Vaccination?, by Varvara A Ryabkova, Leonid P Churilov and Yehuda Shoenfeld in Int. J. Mol. Sci. 2019, 20(20), 5164; [https://doi.org/10.3390/ijms20205164] … Continue reading

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Open trial of Vitamin B12 nasal drops in adults with ME/CFS

Open trial of Vitamin B12 nasal drops in adults with Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome: comparison of responders and non-responders, by C (Linda) MC van Campen, Klaas Riepma and Frans C Visser in Frontiers in Pharmacology,  20 September 2019 [ … Continue reading

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The efficacy & safety of Myelophil, an ethanol extract mixture of Astragali Radix & Salviae Radix, for CFS

The efficacy and safety of Myelophil, an Ethanol extract mixture of Astragali Radix and Salviae Radix, for Chronic Fatigue Syndrome: a randomized clinical trial, by Jin-Yong Joung, Jin-Seok Lee, Jung-Hyo Cho, Dong-Soo Lee, Yo-Chan Ahn and Chang-Gue Son in Front. … Continue reading

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Revised Cochrane review of exercise treatments for CFS

WAMES statement: The revised Cochrane review on exercise therapy for ME & CFS has taken positive steps to acknowledge the limitations of the research into exercise therapy that they previously promoted, and especially the lack of research into potential harms.  … Continue reading

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Work rehabilitation & medical retirement for ME/CFS patients

Work rehabilitation and medical retirement for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome patients. A review and appraisal of diagnostic strategies by Mark Vink and Friso Vink-Niese in Diagnostics 2019, 9(4), 124;  [https://doi.org/10.3390/diagnostics9040124] Published: 20 September 2019   Review abstract: Myalgic Encephalomyelitis/Chronic Fatigue … Continue reading

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Quantitative electroencephalographic assessment of ME/CFS

Quantitative Electroencephalographic assessment of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome: support for a novel diagnostic protocol, by Andrew E Pellegrini. Laurentian University: a thesis submitted in partial fulfillment for the Honors degree Bachelor of Science 2019   Research abstract: The … Continue reading

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Towards a biomarker: Rethinking ME/CFS diagnostic reference intervals via machine learning, & the utility of activin B for defining symptom severity

Rethinking ME/CFS diagnostic reference intervals via machine learning, and the utility of activin B for defining symptom severity, by Brett A. Lidbury, Badia Kita, Alice M Richardson, Donald P Lewis, Edwina Privitera, Susan Hayward, David de Kretser and Mark Hedger … Continue reading

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ME/CFS: From pathophysiological insights to novel therapeutic opportunities

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: from pathophysiological insights to novel therapeutic opportunities, by Gerwyn Morris, Basant K Puri, Adam J Walker, Michael Maes, Andre F Carvalho, Ken Walder, Catherine Mazza, Michael Berk in Pharmacological Research [Available online 8 September 2019] https://doi.org/10.1016/j.phrs.2019.104450 … Continue reading

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Unexplained exertional intolerance associated with impaired systemic oxygen extraction

The researchers reviewed invasive cardiopulmonary test results of 313 patients with unexplained exertional intolerance. The paper focuses mainly on a small subset of patients: “We identified a cohort of patients whose exercise limitation is due only to systemic oxygen extraction, … Continue reading

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