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Cancer doctor Dagfinn Øgreid has treated ME patients with rituximab
Blog article: Offers private ME treatment with cancer drugs – scientists react, by Anne Grete Storvik, Nov 23 2015 in Dagensmedicin [ translated by Google translate] A private clinic in Sandnes offers treatment for ME with the cancer drug rituximab. Patients pay … Continue reading
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Tagged autoimmune disorders, Dr Dagfinn Øgreid, Dr Oystein Fluge, immunomodulatory drug, Norway, Prof Olav Mella, rituximab
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UK rituximab trial fundraising total almost reached
Invest in ME has announced the latest fundraising total for the rituximab/B-cell research, which is a great boost as the research team at UCL are about to visit and discuss the subject with Dr Fluge and Professor Mella in Haukeland University Hospital, … Continue reading
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Tagged B-cell, Dr Oystein Fluge, IiME, Invest in ME, Prof Olav Mella, rituximab, UCL, University College London
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Elevated autoantibodies found in CFS subgroup
Research highlights: β adrenergic and muscarinic acetylcholine receptor autoantibodies are elevated in a subset of patients with Chronic Fatigue Syndrome (CFS). Elevated autoantibodies in CFS correlate with elevated IgG1-3 subclass levels, thyreoperoxidase and ANA antibodies and T cell activation. In … Continue reading
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Tagged autoantibodies, autoimmune disorders, Dr Oystein Fluge, Prof Olav Mella, Receptors, rituximab, subgroup, T-cell
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Rituximab leads to B-cell depletion and remission in ME/CFS
Research abstract: Background: Myalgic Encephalopathy/Chronic Fatigue Syndrome (ME/CFS) is a disease of unknown etiology. We previously reported a pilot case series followed by a small, randomized, placebo-controlled phase II study, suggesting that B-cell depletion using the monoclonal anti-CD20 antibody rituximab … Continue reading
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Tagged antibodies, B-cell, Dr Olav Mella, Dr Oystein Fluge, New Scientist, rituximab
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Fluge & Mella’s patent application for a CFS treatment
Excerpt from patent application: Inventors: Øystein Fluge & Olav Mella Date of publication 26 11 2014 Nitric oxide donor for the treatment of chronic fatigue syndrome. Description [0001] The present invention relates in a first aspect to a nitric oxide donor for … Continue reading
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Tagged Dr Olav Mella, Dr Oystein Fluge, Nitric oxide donor, NO donor, patent
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Rituximab interviews
Two Norwegian scientists, Øystein Fluge and Olav Mella, who have been researching the effects of an anti-lymphoma drug called Rituximab on people with ME/CFS, talked about their work on the BBC Radio Cambridgeshire programme ‘Naked Scientists’ on Sunday, 22 March. … Continue reading
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Tagged autoimmune disorders, BBC radio, blood vessels, cardiopulmonary tests, Cyclophosphamide, Dr Olav Mella, Dr Oystein Fluge, endothelial dysfunction, exercise tests, gastrointestinal disorder, gene expression, immunomodulatory drug, rituximab, Teresa Grøtan
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Norwegian Rituximab trial update
The Norwegian multicenter Rituximab study begins The long-awaited Norwegian phase III study of Rituximab as a treatment for ME/CFS is now getting off the ground. The study is led by the oncologists Prof Olav Mella and Dr Øystein Fluge at … Continue reading
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Tagged Dr Jo Cambridge, Dr Oystein Fluge, Norway, Prof Jonathan Edwards, Prof Olav Mella, rituximab
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Update on rituximab
Drs Oystein Fluge and Olav Mella have been given 2 million Norwegian Kroners (approx. £220,000) to help fund a larger multi-centre follow-up study to confirm their findings that some people with ME had benefited from the immune modulator rituximab. This … Continue reading
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Tagged Dr Olav Mella, Dr Oystein Fluge, rituximab
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