Tag Archives: immune dysfunction

Low NK cell activity differs in ME/CFS & MS

Posted on 09/22/2015 by wames

Research abstract: Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) and Multiple Sclerosis (MS) patients suffer from debilitating fatigue which is not alleviated by rest. In addition to the fatigue related symptoms suffered by CFS/ME and MS patients, dysfunction of the immune system … Continue reading →

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Low NK Cell activity in CFS and is related to severity

Posted on 09/21/2015 by wames

Review abstract: Background: Natural killer (NK) cells act as an immune surveillance against invading pathogens and tumors. NK cell cytotoxicity (NKCC) has been reported to be decreased in patients with CFS. Methods: The objective of this review was to conduct … Continue reading →

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Immune dysfunction differs in moderate and severe CFS/ME over time

Posted on 09/21/2015 by wames

Research abstract: Background: Research has identified immunological abnormalities in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME), a heterogeneous illness with an unknown cause and absence of diagnostic test. There have been no CFS/ME studies examining innate and adaptive immune cells longitudinally in … Continue reading →

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Dr Jacob Teitelbaum overview of research into CFS & ME

Posted on 07/17/2015 by wames

Numerous studies, including research on immunologic and hormonal changes, confirm that fibromyalgia and chronic fatigue syndrome (CFS) are painfully real illnesses. Though many insurance companies continue to deny that science so they can avoid paying healthcare and disability costs, this … Continue reading →

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Immune and inflammation related genes in CFS

Posted on 07/03/2015 by wames

Research abstract: Recent evidence suggests immune and inflammatory alterations are important in chronic fatigue syndrome (CFS). This study was done to explore the association of functionally important genetic variants in inflammation and immune pathways with CFS. Peripheral blood DNA was … Continue reading →

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Dysfunction found in innate and adaptive immune systems in CFS/ME

Posted on 06/10/2015 by wames

Research abstract: Background: Abnormal immune function is often an underlying component of illness pathophysiology and symptom presentation. Functional and phenotypic immune-related alterations may play a role in the obscure pathomechanism of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). The objective of this … Continue reading →

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B cells in the immune systems of people with CFS

Posted on 03/12/2015 by wames

Research abstract Limited immunological changes have been previously reported in B cell phenotype in Chronic Fatigue Syndrome (CFS) patients, so there is no clear established role of B cells in the pathophysiology of CFS patients. The aim of this study … Continue reading →

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Natural killer cells in severe CFS

Posted on 05/31/2014 by wames

Abstract Maintenance of health and physiological homeostasis is a synergistic process involving tight regulation of proteins, transcription factors and other molecular processes. The immune system consists of innate and adaptive immune cells that are required to sustain immunity. The presence … Continue reading →

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Immune dysregulation in CFS similar to autoimmune disorders

Posted on 03/12/2014 by wames

Abstract Perturbations in immune processes are a hallmark of a number of autoimmune and inflammatory disorders. Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is an inflammatory disorder with possible autoimmune correlates, characterized by reduced NK cell activity, elevations in regulatory T cells … Continue reading →

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Immune dysfunction worse in severe CFS patients

Posted on 03/12/2014 by wames

Abstract Objective: Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a disabling illness, characterized by persistent, debilitating fatigue and a multitude of symptoms. Immunological alterations are prominent in CFS/ME cases, however little is known about the relationship between CFS/ME severity and the … Continue reading →

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