Tag Archives: immune dysfunction

Immune and inflammation related genes in CFS

Research abstract: Recent evidence suggests immune and inflammatory alterations are important in chronic fatigue syndrome (CFS). This study was done to explore the association of functionally important genetic variants in inflammation and immune pathways with CFS. Peripheral blood DNA was … Continue reading

Posted in News | Tagged , , , | Comments Off on Immune and inflammation related genes in CFS

Dysfunction found in innate and adaptive immune systems in CFS/ME

Research abstract: Background: Abnormal immune function is often an underlying component of illness pathophysiology and symptom presentation. Functional and phenotypic immune-related alterations may play a role in the obscure pathomechanism of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). The objective of this … Continue reading

Posted in News | Tagged , , , , | Comments Off on Dysfunction found in innate and adaptive immune systems in CFS/ME

B cells in the immune systems of people with CFS

Research abstract Limited immunological changes have been previously reported in B cell phenotype in Chronic Fatigue Syndrome (CFS) patients, so there is no clear established role of B cells in the pathophysiology of CFS patients. The aim of this study … Continue reading

Posted in News | Tagged , , , | Comments Off on B cells in the immune systems of people with CFS

Natural killer cells in severe CFS

Abstract Maintenance of health and physiological homeostasis is a synergistic process involving tight regulation of proteins, transcription factors and other molecular processes. The immune system consists of innate and adaptive immune cells that are required to sustain immunity. The presence … Continue reading

Posted in News | Tagged , , , , | Comments Off on Natural killer cells in severe CFS

Immune dysregulation in CFS similar to autoimmune disorders

Abstract Perturbations in immune processes are a hallmark of a number of autoimmune and inflammatory disorders. Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is an inflammatory disorder with possible autoimmune correlates, characterized by reduced NK cell activity, elevations in regulatory T cells … Continue reading

Posted in News | Tagged , , , | Comments Off on Immune dysregulation in CFS similar to autoimmune disorders

Immune dysfunction worse in severe CFS patients

Abstract Objective: Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a disabling illness, characterized by persistent, debilitating fatigue and a multitude of symptoms. Immunological alterations are prominent in CFS/ME cases, however little is known about the relationship between CFS/ME severity and the … Continue reading

Posted in News | Tagged , | Comments Off on Immune dysfunction worse in severe CFS patients

Cognitive dysfunction causes fatigue and depression in ME/CFS

Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by persistent emotional, mental, and physical fatigue accompanied by a range of neurological, autonomic, neuroendocrine, immune, and sleep problems. Research has shown that psychosocial factors such as anxiety and depression as … Continue reading

Posted in News | Tagged , , , , , , | Comments Off on Cognitive dysfunction causes fatigue and depression in ME/CFS