Tag Archives: peripheral blood mononuclear cells

Mitochondrial complex activity in permeabilised cells of CFS patients using two cell types

Mitochondrial complex activity in permeabilised cells of CFS patients using two cell types, by Cara Tomas, Audrey E Brown, Julia L Newton and Joanna L Elson in Peer Journal, 1 Mar 2019   Article abstract: Abnormalities in mitochondrial function have … Continue reading

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miRNA profiling of circulating EVs in ME/CFS

miRNA profiling of circulating EVs in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS) by Eloy Almenar-Pérez, Lubov Nathanson, Teresa Sánchez-Fito, Leonor Sarria, Germán Cerdá-Olmedo, Elisa Oltra  in Journal of Extracellular Vesicles, suppl. Supplement 1; Abingdon Vol. 7,  (2018): 139.   Research abstract: Background: … Continue reading

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Cellular bioenergetics is impaired in patients with CFS

Research abstract: Cellular bioenergetics is impaired in patients with chronic fatigue syndrome, by Cara Tomas, Audrey Brown, Victoria Strassheim, Joanna Elson, Julia Newton, Philip Manning in PLOSone [Published: October 24, 2017] Chronic fatigue syndrome (CFS) is a highly debilitating disease of … Continue reading

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MEA to fund new research into biomarkers and markers of disease activity in people with severe ME/CFS

ME Association announcement, 20 December 2016: MEA to fund new research into biomarkers and markers of disease activity in people with severe ME/CFS We are pleased to announce that – following the normal rigorous peer review procedures – the MEA Ramsay … Continue reading

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Mast cell dysfunction in ME/CFS

Research abstract: BACKGROUND: Mast cells (MCs) mediate inflammation through neuropeptides and cytokines, along with histamine and reactive oxygen species (ROS). Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is an illness characterized by an unexplained disabling fatigue with multiple physiological impairments as well as … Continue reading

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