Tag Archives: Natural Killer cells

Association of T & NK cell phenotype with the diagnosis of ME/CFS

Research abstract: Association of T and NK cell phenotype with the diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), by Jose Luis Rivas, Teresa Palencia, Guerau Fernández, Milagros Garcia in Front. Immunol., 09 May 2018 Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is … Continue reading

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Rituximab impedes natural killer cell function in CFS/ME patients

Research abstract: Rituximab impedes natural killer cell function in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients: A pilot in vitro investigation by Natalie Eaton, Hélène Cabanas, Cassandra Balinas, Anne Klein, Donald Staines and Sonya Marshall-Gradisnik in BMC Pharmacology and Toxicology 2018 19:12 [Published: … Continue reading

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Longitudinal associations of lymphocyte subsets with clinical outcomes in CFS

Research abstract: Longitudinal associations of lymphocyte subsets with clinical outcomes in chronic fatigue syndrome, by  Melissa L. Mehalick, Karen B. Schmaling , Daniel E. Sabath, & Dedra S. Buchwald in Fatigue: Biomedicine, Health & Behavior 2018 pp 1-12  [Published online: 12 Jan 2018] Background: … Continue reading

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Australian researchers discover abnormalities in immune cell receptors in ME/CFS

Huffington Post Australia, by Luke Cooper, 22 Feb 2017: Queensland Scientists Make Chronic Fatigue Syndrome Research Breakthrough The condition has been linked to abnormal immune system cells. Queensland scientists have linked Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis … Continue reading

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Calcium mobilisation in natural killer cells & cell cytotoxicity in CFS/ME

Research abstract: Transient receptor potential melastatin subfamily 3 (TRPM3) ion channels play a role in calcium (Ca2+ ) cell signalling. Reduced TRPM3 has been identified in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) patients. However, the significance of TRPM3 and association with … Continue reading

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Dysregulation of protein kinase gene expression in NK Cells in CFS

Research abstract: BACKGROUND: The etiology and pathomechanism of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) are unknown. However, natural killer (NK) cell dysfunction, in particular reduced NK cytotoxic activity, is a consistent finding in CFS/ME patients. Previous research has reported significant changes … Continue reading

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No difference found in difference in KIR expression in ME/CFS

Research abstract: Killer cell immunoglobulin-like receptor (KIR) genes encode for activating and inhibitory surface receptors, which are correlated with the regulation of Natural Killer (NK) cell cytotoxic activity. Reduced NK cell cytotoxic activity has been consistently reported in Chronic Fatigue … Continue reading

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Natural killer cell & SNP dysfunction in ME/CFS

Research abstract: Aim: The aim of this paper was to determine natural killer (NK) cytotoxic activity and if single nucleotide polymorphisms (SNPs) and genotypes in transient receptor potential (TRP) ion channels and acetylcholine receptors (AChRs) were present in isolated NK … Continue reading

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Natural Killer Cells in CFS/ME & Multiple Sclerosis

Research abstract: Patients with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and multiple sclerosis (MS) suffer from debilitating fatigue which is not alleviated by rest. In addition to the fatigue-related symptoms suffered by patients with CFS/ME and MS, dysfunction of the immune … Continue reading

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Potential diagnostic biomarkers in Natural Killer cells of patients with CFS/ ME

Research abstract: BACKGROUND: Chronic Fatigue Syndrome (CFS/ME) is a complex multisystem disease of unknown aetiology which causes debilitating symptoms in up to 1% of the global population. Although a large cohort of genes have been shown to exhibit altered expression … Continue reading

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