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Research review: Brainstem abnormalities in ME/CFS… evaluation of MRI findings
Brainstem abnormalities in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A scoping review and evaluation of Magnetic Resonance Imaging findings, by Todd Nelson, Lan-Xin Zhang, Hui Guo, Luis Nacul, Xiaowei Son in Frontiers in Neurology Vol 12, p 769511, Dec 2021 [doi:10.3389/fneur.2021.769511] Review … Continue reading
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Tagged astrocyte dysfunction, brainstem, cerebral perfusion impairment, Functional connectivity, gray matter, impaired nerve conduction, Magnetic Resonance Imaging, MRI, Neuroinflammation, white matter
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Grey and white brain matter differences in CFS
Research abstract: Grey and white matter differences in Chronic Fatigue Syndrome – a voxel-based morphometry study, by Andreas Finkelmeyer, Jiabao He, Laura Maclachlan, Stuart Watson, Peter Gallagher, Julia L. Newton, Andrew M. Blamire in NeuroImage: Clinical, Volume 17, 2018, Pages 24-30 [Preprint Available online 28 September … Continue reading
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Tagged amygdala, Andrew M Blamire, brainstem, grey matter volume, Jiabao He, Laura Maclachlan, midbrain, Peter Gallagher, Prof Andreas Finkelmeyer, Prof Julia Newton, Stuart Watson, voxel based morphometry, white matter
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Central nervous system findings in CFS
Review abstract: CNS findings in chronic fatigue syndrome and a neuropathological case report Kimberly Ferrero, Mitchell Silver, Alan Cocchetto, Eliezer Masliah, Dianne Langford in Journal of Investigative Medicine Vol 65 Issue 4 [published 6 April 2017] Chronic fatigue syndrome (CFS) is characterized as a persistent, debilitating complex disorder of unknown … Continue reading
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Tagged Alan Cocchetto, autopsy, Central Nervous System, CNS, Dr Dianne Langford, Eliezer Masliah, Kimberly Ferrero, Mitchell Silver, white matter
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Six year study of abnormal brain changes in ME/CFS
ME Australia blog post, by Sasha Nimmo, 12 July 2016: Six year study of abnormal brain changes in chronic fatigue syndrome patients An Australian six year study evaluating progressive brain changes associated with chronic fatigue syndrome (Fukuda and Canadian Consensus … Continue reading
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Tagged Australia, brain dysfunction, Dr Sonya Marshall-Gradisnik, Magnetic Resonance Imaging, MRI, Sasha Nimmo, white matter
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Brain white matter abnormalities in ME/CFS
ME Research UK research article, by Dr Neil Abbot, 25 May 2016: White matter abnormalities Most studies in ME/CFS are cross-sectional in nature – researchers look at patients and controls at one point in time and make comparisons between the … Continue reading
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Tagged brain dysfunction, Dr Neil Abbot, ME Research UK, white matter
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Progressive brain changes in patients with CFS
Research abstract: PURPOSE: To examine progressive brain changes associated with chronic fatigue syndrome (CFS). MATERIALS AND METHODS: We investigated progressive brain changes with longitudinal MRI in 15 CFS and 10 normal controls (NCs) scanned twice 6 years apart on the same … Continue reading
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Tagged brain dysfunction, Dr Sonya Marshall-Gradisnik, inferior fronto-occipital fasciculus, Magnetic Resonance Imaging, MRI, white matter, ZY Shan
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Fatigue may involve abnormal function of the motor system
Research abstract: Although the prevalence of chronic fatigue is approximately 20% in healthy individuals, there are no studies of brain structure that elucidate the neural correlates of fatigue outside of clinical subjects. We hypothesized that fatigue without evidence of disease … Continue reading
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Tagged basal ganglia, brain, chronic fatigue, fMRI, motor system, white matter
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MRI shows differences between CFS and depression
Research article: White matter (WM) involvement in chronic fatigue syndrome (CFS) was assessed using voxel-based regressions of brain MRI against CFS severity scores and CFS duration in 25 subjects with CFS and 25 normal controls (NCs). As well as voxel-based … Continue reading
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Tagged anxiety, depression, impaired nerve conduction, white matter
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