Category Archives: News

Gait automaticity in women with CFS

Research abstract: Patients with chronic fatigue syndrome (CFS) report difficulties walking for a prolonged period of time. This study compares gait automaticity between women with CFS and nondisabled controls. The “stops walking with eyes closed with secondary cognitive task” test … Continue reading

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ME Research UK research projects

ME Research UK has produced another print-run of their 32-page special edition of Breakthrough magazine entitled ‘£1 million of biomedical research: an overview of the projects you have funded’. If you would like a (free) hard copy in the post, simply … Continue reading

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Neuroimaging of Central Sensitivity Syndromes

Research abstract: Central sensitivity syndromes are characterized by distressing symptoms, such as pain and fatigue, in the absence of clinically obvious pathology. The scientific underpinnings of these disorders are not currently known. Modern neuroimaging techniques promise new insights into mechanisms … Continue reading

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Abnormal cerebral blood flow found in ME/CFS by ASL fMRI

Research abstract: BACKGROUND Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disorder characterized by severe fatigue and neurocognitive dysfunction. Recent work from our laboratory and others utilizing arterial spin labeling functional magnetic resonance imaging (ASL) indicated that ME/CFS patients have … Continue reading

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The effect of significant other responses on CFS symptom fluctuations

Research abstract: Objective: Significant other responses to patients’ symptoms are important for patient illness outcomes in chronic fatigue syndrome (CFS/ME); negative responses have been associated with increased patient depression, whilst increased disability and fatigue have been associated with solicitous significant other responses. The current … Continue reading

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The effect of subjective sleep on fatigue in CFS

Research abstract: Study Objectives: This study aimed to (1) examine the relationship between subjective and actigraphy-defined sleep, and next-day fatigue in chronic fatigue syndrome (CFS); and (2) investigate the potential mediating role of negative mood on this relationship. We also … Continue reading

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Dr David Maughan discusses ME, it’s treatment and it’s difficult politics

Researcher Dr. David Maughan of the University of Vermont, and Advocate Rik Carlson discuss the disease, it’s treatment, and the difficult politics surrounding this disease in particular, in the Paradigms blog: What is Myalgic Encephalomyelitis, also known as Chronic Fatigue … Continue reading

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Rethinking childhood adversity in CFS

Research abstract: Objectives: Previous studies have consistently shown increased rates of childhood adversity in chronic fatigue syndrome (CFS). However, such aetiopathogenic studies of CFS are potentially confounded by co-morbidity and misdiagnosis particularly with depression. We used a modelling approach with existing data and data … Continue reading

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Anti-citrullinated protein antibodies in CFS

The Vermont CFIDS Association reports on a recent pilot study and invites contributions to enable further research: While preliminary, the results from this University of Vermont study is the first evidence for the potential existence of autoantibodies in ME/CFS, indicative … Continue reading

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Junior doctors’ experiences of managing patients with MUS

Research abstract: Objectives:  To explore junior doctors’ knowledge about and experiences of managing patients with medically unexplained symptoms (MUS) and to seek their recommendations for improved future training on this important topic about which they currently receive little education. Design: … Continue reading

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