Category Archives: News

A dozen different diseases? Prof Stephen Holgate calls for radical change in ME/CFS research

ME/CFS probably isn’t one disease, or even a few different ones – but could be as many as fifteen. So said Professor Stephen Holgate, Chair of the UK Research Collaborative (CMRC), when he addressed the Forward ME Group in the … Continue reading

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Paralysis in ME

Study abstract Paralysis is a symptom that is rarely highlighted in the literature for ME, yet is found amongst the most severely ill ME population and even some of those not so severely affected. My wife has experienced it for … Continue reading

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Self-management can improve fatigue

Research abstract Objective: To assess the efficacy of brief fatigue self-management (FSM) for medically unexplained chronic fatigue (UCF) and chronic fatigue syndrome (CFS) in primary care. Methods: A randomized controlled design was used wherein 111 patients with UCF or CFS … Continue reading

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Eye movement dysfunction in ME/CFS

Research abstract Background: People who suffer from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) often report that their eye movements are sluggish and that they have difficulties tracking moving objects. However, descriptions of these visual problems are based solely on patients’ self-reports of … Continue reading

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Human herpesvirus-6 infection can be inherited

HHV-6 has been found in people with ME. Abstract Human herpesvirus-6 (HHV-6)A and 6B are ubiquitous betaherpesviruses viruses with lymphotropic and neurotropic potential. As reported earlier, these viruses establish latency by integration into the telomeres of host chromosomes. Chromosomally integrated … Continue reading

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Delayed recovery in CFS can affect exercise testing results

Research abstract Objectives  –  Reduced functional capacity and post-exertional fatigue following physical activity are hallmark symptoms of chronic fatigue syndrome (CFS) and may even qualify for biomarker status. That these symptoms are often delayed may explain the equivocal results for clinical … Continue reading

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Treatment of sleep disorder may not improve fatigue in CFS

Abstract Chronic fatigue syndrome (CFS) is a disabling condition characterized by severe fatigue lasting for more than six months and the presence of at least four out of eight minor criteria. Sleep disturbance presenting as unrefreshing or nonrestorative sleep is … Continue reading

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Flu vaccination alters gene expression in CFS

Research abstract Vaccines have been shown to cause differential expression of genes and increase antibody titers against antigens. Influenza vaccines may have an effect on unexplained disorders such as Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). Immunological changes have been identified following … Continue reading

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Mitochondrial dysfunction differs in CFS and FM

Research abstract Chronic fatigue syndrome (CFS) and fibromyalgia (FM) are complex and serious illnesses that affect approximately 2.5% and 5% of the general population worldwide, respectively. The etiology is unknown; however, recent studies suggest that mitochondrial dysfunction has been involved … Continue reading

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Reasons for poor experiences of rehabilitation therapies

Review abstract Purpose:  First, to explore the experiences of people with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) of rehabilitation therapies so as to build an understanding of reasons for the discrepancy between the notably mixed experiences regarding effectiveness reported in patient … Continue reading

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