Tag Archives: fatigue
Do MS & ME/CFS co-exist in the same patients?
Research abstract INTRODUCTION: Fatigue is a major cause of disability and handicap in Multiple Sclerosis (MS) patients. The management of this common problem is often difficult. Chronic Fatigue Syndrome (CFS/ME) is another common cause of fatigue which is prevalent in … Continue reading
Prolonged fatigue [CFS] & cytokines post-West Nile Virus infection in USA
Simon McGrath comments on a research paper: Evaluation of Prolonged Fatigue Post–West Nile Virus Infection and Association of Fatigue with Elevated Antiviral and Proinflammatory Cytokines Extract: 31% of the cohort were fatigued at follow-up (44/140) and “Of those with fatigue … Continue reading
Fatigue in OI subgroup improves with modafinil
Abstract Many patients who suffer from orthostatic intolerance (OI) may also have severe fatigue and extreme exercise intolerance. In some of these patients, fatigue may be so severe that they are unable to maintain employment. In some, even the activities … Continue reading
Decreased basal ganglia function and relationship to fatigue in CFS
Abstract Reduced basal ganglia function has been associated with fatigue in neurologic disorders, as well as in patients exposed to chronic immune stimulation. Patients with chronic fatigue syndrome (CFS) have been shown to exhibit symptoms suggestive of decreased basal ganglia … Continue reading
Mitochondrial dysfunction and fatigue review
Abstract Fatigue is often described by patients as a lack of energy, mental or physical tiredness, diminished endurance, and prolonged recovery after physical activity. Etiologic mechanisms underlying fatigue are not well understood; however, fatigue is a hallmark symptom of mitochondrial … Continue reading
Cognitive dysfunction causes fatigue and depression in ME/CFS
Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by persistent emotional, mental, and physical fatigue accompanied by a range of neurological, autonomic, neuroendocrine, immune, and sleep problems. Research has shown that psychosocial factors such as anxiety and depression as … Continue reading
Childhood stressors in the development of CFS and FM
Review Abstract Background Chronic fatigue syndrome (CFS) and fibromyalgia (FM) are both highly prevalent conditions associated with extreme disability and with the development of co-morbid psychiatric disorders, such as depression and anxiety. Childhood stressors have been shown to induce persistent … Continue reading
Fatigue in cancer and CFS
Abstract BACKGROUND Androgen deprivation therapy (ADT) often worsens fatigue in patients with prostate cancer, producing symptoms similar to chronic fatigue syndrome (CFS). Comparing expression (mRNA) of many fatigue-related genes in patients with ADT-treated prostate cancer versus with CFS versus healthy … Continue reading
Self-management can improve fatigue
Research abstract Objective: To assess the efficacy of brief fatigue self-management (FSM) for medically unexplained chronic fatigue (UCF) and chronic fatigue syndrome (CFS) in primary care. Methods: A randomized controlled design was used wherein 111 patients with UCF or CFS … Continue reading
Treatment of sleep disorder may not improve fatigue in CFS
Abstract Chronic fatigue syndrome (CFS) is a disabling condition characterized by severe fatigue lasting for more than six months and the presence of at least four out of eight minor criteria. Sleep disturbance presenting as unrefreshing or nonrestorative sleep is … Continue reading
