Tag Archives: Prof Donald Staines
Protein kinase gene dysfunction in severe CFS/ME
Research abstract: Background: The etiology and pathomechanism of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) are unknown. However, natural killer (NK) cell dysfunction, in particular reduced NK cytotoxic activity, is a consistent finding in CFS/ME patients. Previous research has reported significant changes … Continue reading
Mast cell dysfunction in ME/CFS
Research abstract: BACKGROUND: Mast cells (MCs) mediate inflammation through neuropeptides and cytokines, along with histamine and reactive oxygen species (ROS). Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is an illness characterized by an unexplained disabling fatigue with multiple physiological impairments as well as … Continue reading
No difference found in difference in KIR expression in ME/CFS
Research abstract: Killer cell immunoglobulin-like receptor (KIR) genes encode for activating and inhibitory surface receptors, which are correlated with the regulation of Natural Killer (NK) cell cytotoxic activity. Reduced NK cell cytotoxic activity has been consistently reported in Chronic Fatigue … Continue reading
CFS/ME cell discovery may hold key to treatment
Griffith University Media release, by Louise Durack, 9 June 2016: Chronic Fatigue Syndrome cell discovery may hold key to treatment: Chronic Fatigue Syndrome researchers have discovered a cell receptor which could be a key contributing factor to CFS, providing a … Continue reading
Systematic review of drug therapies for CFS/ME finds no drugs universally effective
Review abstract: Purpose: The pathogenesis of chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) is complex and remains poorly understood. Evidence regarding the use of drug therapies in CFS/ME is currently limited and conflicting. The aim of this systematic review was to examine the existing evidence on … Continue reading
Griffith University Queensland marks ME Awareness day
Scimex article, 4 May 2016: Aussie scientists find genetic changes associated with chronic fatigue syndrome (CFS) Immunology and Immunogenetics Insights Australian researchers say they’ve found genetic changes associated with chronic fatigue syndrome (CFS, also known as Myalgic Encephalomyelitis or ME). … Continue reading
