Tag Archives: Prof Julia Newton
Understanding severely affected CFS: the gravity of the situation
Review abstract: Understanding severely affected chronic fatigue syndrome (CFS): The gravity of the situation, by Victoria Strassheim, Robert Ballantine, Katie L. Hackett, James Frith, Julia L. Newton in Physical Therapy Reviews [Preprint May 25, 2017] Objective: To describe how the effects of gravity … Continue reading
UK MEGA project update on funding applications & patient advisory group
MEGA research blog post, by Sonya Chowdhury, 29 March 2017: Our latest funding application and Patient Advisory Group update An update from the Scientific Team and Patient Advisory Group. First the bad news: unfortunately our preliminary application to Wellcome, submitted … Continue reading
Clinically proven mtDNA mutations are not common in CFS
Research abstract: Background: Chronic Fatigue Syndrome (CFS) is a prevalent debilitating condition tat affects approximately 250,000 people in the UK. There is growing interest in the role of mitochondrial function and mitochondrial DNA (mtDNA) variation in CFS. It is now … Continue reading
Standard research criteria would aid ME/CFS research
Research abstract: Background: The Institute of Medicine (IOM) recently developed clinical criteria for what had been known as chronic fatigue syndrome. Given the broad nature of the clinical IOM criteria, there is a need for a research definition that would … Continue reading
Two year follow-up of sleep diaries & polysomnography in CFS
Research abstract: Background: Chronic fatigue syndrome (CFS) is a prevalent and debilitating symptom complex of unknown aetiology. Up to 96.8% of people with CFS report unrefreshing sleep and many describe, in qualitative interviews, changes in sleep over the course of their illness. Purpose: … Continue reading
Treatment of insomnia reduces fatigue in CFS
Research abstract: Background: Effectiveness of cognitive behavioural therapy for insomnia (CBT-I) has not been explored in Chronic Fatigue Syndrome (CFS), a condition where disturbed sleep is a principal symptom. This study aimed to report feasibility, acceptability and initial effectiveness of … Continue reading
Assessing reduction in activity levels in ME/CFS
Research abstract: Background: Myalgic encephalomyelitis and chronic fatigue syndrome have case definitions with varying criteria, but almost all criteria require an individual to have a substantial reduction in activity level. Unfortunately, a consensus has not been reached regarding what constitutes substantial … Continue reading
Reduced cardiac volumes in ME/CFS
ME Research UK article: Reduced cardiac volumes in chronic fatigue syndrome associate with plasma volume but not length of disease: a cohort study Over the years, a number of reports in the scientific literature have pointed to the presence of … Continue reading
Cardiac abnormality and low blood volume confirmed in CFS
Research abstract: Objectives: To explore potential mechanisms that underpin the cardiac abnormalities seen in chronic fatigue syndrome (CFS) using non-invasive cardiac impedance, red cell mass and plasma volume measurements. Methods Crdiac MR (MR) examinations were performed using 3 T Philips Intera … Continue reading
